ACIFRAN Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Antihyperlipopro-teinemic.
Trademarks
Reductol (Wyeth-Ayerst).
Biologische Aktivit?t
Hypolipidaemic agent; more potent than nicotinic acid and clofibrate. Full and potent agonist at the human orphan GPCR HM74A/GPR109A and GPR109B (EC 50 values are 1.3? and 4.2 μ M respectively). In vivo, reduces serum triglycerides and circulating LDL-cholesterol without affecting liver weight or liver enzymes.
ACIFRAN Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte