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N-Boc-4-piperidinemethanol

N-Boc-4-piperidinemethanol Struktur
123855-51-6
CAS-Nr.
123855-51-6
Englisch Name:
N-Boc-4-piperidinemethanol
Synonyma:
TERT-BUTYL 4-(HYDROXYMETHYL)PIPERIDINE-1-CARBOXYLATE;N-BOC-piperidine-4-methanol;BOC-PIC(4)-OL;BUTTPARK 75\50-52;N-Boc-4-piperidineMe;Boc-4-Piperidine methanol;N-BOC-piperidin-4-Methanol;N-BOC-4-PIPERIDINEMETHANOL;BOC-ISONICOT(HEXAHYDRO)-OL;1-BOC-4-PIPERIDINEMETHANOL
CBNumber:
CB2100290
Summenformel:
C11H21NO3
Molgewicht:
215.29
MOL-Datei:
123855-51-6.mol

N-Boc-4-piperidinemethanol Eigenschaften

Schmelzpunkt:
78-82 °C (lit.)
Siedepunkt:
308.0±15.0 °C(Predicted)
Dichte
1.059±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
L?slichkeit
soluble in Methanol
Aggregatzustand
Powder
pka
14.94±0.10(Predicted)
Farbe
White to brown
InChI
InChI=1S/C11H21NO3/c1-11(2,3)15-10(14)12-6-4-9(8-13)5-7-12/h9,13H,4-8H2,1-3H3
InChIKey
CTEDVGRUGMPBHE-UHFFFAOYSA-N
SMILES
N1(C(OC(C)(C)C)=O)CCC(CO)CC1
CAS Datenbank
123855-51-6(CAS DataBase Reference)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xi
S-S?tze: 24/25
WGK Germany  3
HazardClass  IRRITANT
HS Code  29339900
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitssch?dlich bei Verschlucken. Akute Toxizit?t oral Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P270, P301+P312, P330, P501
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
Sicherheit
P264 Nach Gebrauch gründlich waschen.
P264 Nach Gebrauch gründlich waschen.
P270 Bei Gebrauch nicht essen, trinken oder rauchen.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P302+P352 BEI BERüHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckm??ig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.
P332+P313 Bei Hautreizung: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen.
P337+P313 Bei anhaltender Augenreizung: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen.
P501 Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen.

N-Boc-4-piperidinemethanol Chemische Eigenschaften,Einsatz,Produktion Methoden

Chemische Eigenschaften

White to light brown solid

Verwenden

N-Boc-4-piperidinemethanol is an important piperidine derivative, which can be used in organic synthesis and pharmaceutical intermediates, It may be used to synthesize:
methyl 5-methoxy-4-(1-methylpiperidin-4-ylmethoxy)-2-nitrobenzoate
N-Boc-4-piperidinecarboxaldehyde
[1-(tert-butoxycarbonyl)piperidin-4-yl]methyl methanesulfonate
Involved in the synthesis of bradycardic agents.

Application

N-Boc-4-piperidinemethanol is a curcumin analogue that binds to the epidermal growth factor receptor (EGFR) and prevents the binding of ligands. In vitro studies have shown that it can inhibit tumor growth and induce apoptosis in cancer cells. The drug is also capable of inhibiting the proliferation of normal cells, which may be due to its ability to recruit EGFR from outside the cell membrane. This process triggers signaling events that lead to cell death.

Allgemeine Beschreibung

N-Boc-4-piperidinemethanol contains a tert-butyloxycarbonyl (t-BOC)-protecting group. It can be synthesized from 4-piperidinemethanol via reaction with di-tert-butyldicarbonate.

N-Boc-4-piperidinemethanol Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

TERT-BUTYL 9-OXO-3-AZASPIRO[5.5]UNDECANE-3-CARBOXYLATE 4-(TOLUENE-4-SULFONYLOXY)-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER N-TERT-BUTOXYCARBONYL-4-(4-TOLUENESULFONYLOXYMETHYL)PIPERIDINE 1-Boc-4-(aminomethyl)piperidine tert-butyl 4-(chloromethyl)piperidine-1-carboxylate tert-butyl 4-(4-bromophenoxymethyl)piperidine-1-carboxylate

N-Boc-4-piperidinemethanol Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 491)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Anhui Yiao New Material Technology Co., Ltd
+86-18033737140 +86-17354101231
 sales1@hbganmiao.com China 227 58
Anhui Dexinjia Biopharm Co., Ltd
+86-531-82375818 +8615064153060
 sales01@jndxj.com China 291 58
Frapp's ChemicalNFTZ Co., Ltd. 		+86 (576) 8169-6106
sales@frappschem.com China 880 50
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806
 sales@capot.com China 29793 60
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512
 info@tianfuchem.com China 21634 55
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
ivan@atkchemical.com China 32956 60
Zjartschem 		+86-571 87238903
jocelynpan@zjarts.com CHINA 988 58
Anqing Chico Pharmaceutical Co., Ltd. 		15380796838
chloewu@chicopharm.cn CHINA 340 58
Shanxi Naipu Import and Export Co.,Ltd 		+86-13734021967 +8613734021967
 kaia@neputrading.com China 1001 58
career henan chemical co 		+86-0371-86658258 +8613203830695
 sales@coreychem.com China 29880 58

123855-51-6()Verwandte Suche:

  • 1-N-BOC-4-HYDROXYMETHYL-PIPERIDINE
  • 1-(TERT-BUTOXYCARBONYL)-4-(HYDROXYMETHYL)PIPERIDINE
  • 1-(TERT-BUTOXYCARBONYL)-4-PIPERIDINEMETHANOL
  • TERT-BUTYL 4-(HYDROXYMETHYL)TETRAHYDRO-1(2H)-PYRIDINECARBOXYLATE
  • N-T-BUTOXYCARBONYL-HEXAHYDROISONICOTINOL
  • N-T-BUTOXYCARBONYL-4-HYDROXYMETHYL-PIPERIDINE
  • N-T-BUTOXYCARBONYL-4-PIPECOLINOL
  • N-T-BUTOXYCARBONYL-4-PIPERIDINEMETHANOL
  • N-(TERT-BUTOXYCARBONYL)-4-(HYDROXYMETHYL)PIPERIDINE
  • N-(TERT-BUTOXYCARBONYL)-4-PIPERIDINEMETHANOL
  • 1-Boc-4-(hydroxymethyl)piperidine 1-Boc-4-piperidinemethanol 1-(tert-Butoxycarbonyl)-4-(hydroxymethyl)piperidine
  • N-Boc-4-piperidineMe
  • 1-piperidinecarboxylic acid, 4-(hydroxymethyl)-, 1,1-dimet
  • N-Boc-4-piperidinemethanol ,97%
  • N-Boc-4-piperidinemethanol,N-tert-Butyloxycarbonyl-4-piperidinemethanol
  • 4-(Hydroxymethyl)piperidine, N-BOC protected 97%
  • 1-Boc-4-(hydroxymethyl)-p...
  • tert-Butyl 4-(hydroxymethyl)piperidine-1-carboxylate, 1-(tert-Butoxycarbonyl)-4-(hydroxymethyl)piperidine
  • t-Butyl 4-(hydroxymethyl)piperidine-1-carboxylate
  • tert-butyl 4-(hydroxyMethyl)piperidin-1-carboxylate
  • N-BOC-piperidin-4-Methanol
  • N-Boc-4-piperidineMethanol, 95+%
  • N - bok - 4 - piperidine Methanol
  • 1-Boc-4-piperidinemethanol Synonyms N-tert-Butyloxycarbonyl-4-piperidinemethanol
  • N-Boc-4-piperidinemethanol 97%
  • 1,1-Dimethylethyl 4-(hydroxymethyl)-1-piperidinecarboxylate
  • n-tert-butyloxycarbonyl-4-piperidinemethanol
  • N-BOC-4-HYDROXYLMETHYLENE-PIPERIDINE
  • N-BOC-4-HYDROXYMETHYLPIPERIDINE
  • N-BOC-4-PIPERIDINEMETHANOL
  • 1-N-Boc-4-piperidinemethanol
  • tert-Butyl 4-(hydroxymethyl)-1-piperidinecarboxylate
  • 1-(TERT-BUTOXYCARBONYL)-4-PYRROLIDINEMETHANOL
  • (1-Boc-Piperidin-4-yl)methanol
  • 1-TERT-BUTOXYCARBONYL-4-PIPERIDINEMETHANOL, N-BOC-4-PIPERIDINEMETHANOL
  • N-BOC-4-HYDROXYMETHYLPIPERDINE
  • N-(tert-Butoxycarbonyl)-4-(Hydroxymethyl)piperidine, 98 %
  • 1-Piperidinecarboxylic acid, 4-(hydroxymethyl)-, 1,1-dimethylethyl ester
  • 1-Boc-4-Hyroxymethyl-Piperidine
  • 4-Hydroxylmethyl-N-( tert-butylcarboxylate)piperidine
  • BUTTPARK 75\50-52
  • BOC-PIC(4)-OL
  • BOC-ISONICOT(HEXAHYDRO)-OL
  • 4-HYDROXYMETHYL-1-TERT-BUTOXYCARBONYLPIPERIDINE
  • 4-HYDROXYMETHYL-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
  • 4-(HYDROXYMETHYL)PIPERIDINE-N-BOC PROTECTED
  • 1-BOC-4-(HYDROXYMETHYL)PIPERIDINE
  • 1-BOC-4-PIPERIDINEMETHANOL
  • tert-Butyl 4-(hydroxymethyl)-1
  • 1-(tert-Butoxycarbonyl)-4-piperidinemethanol >
  • Boc-4-Piperidine methanol
  • N-Boc-4-piperidinyl alcohol
  • N-Boc 4-piperdine methanol
  • N-Boc-4-piperidinemethanol 123855-51-6
  • TERT-BUTYL 4-(HYDROXYMETHYL)PIPERIDINE-1-CARBOXYLATE
  • N-BOC-piperidine-4-methanol
  • 4-Hydroxymethyl-piperidin-1-carboxylic acid tert-butyl ester
  • 123855-51-6
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