HYDROXYFASUDIL MONOHYDROCHLORIDE
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- CAS-Nr.
- 155558-32-0
- Englisch Name:
- HYDROXYFASUDIL MONOHYDROCHLORIDE
- Synonyma:
- Fasudil Hydroxy;Hydroxyfasudil HCl;Fasudil Impurity 7 HCl;Hydroxyfasudil (HA-1100);Hydroxyfasudil HCl (HA1100);Hydroxyfasudil Hydrochloride;Hydroxyfasudil (HA-1100) HCl;HYDROXYFASUDIL MONOHYDROCHLORIDE;Hydroxyfasudil hydrochloride hydrate;HA 1100 hydrochloride (Hydroxyfasudil)
- CBNumber:
- CB1973040
- Summenformel:
- C14H18ClN3O3S
- Molgewicht:
- 343.82902
- MOL-Datei:
- 155558-32-0.mol
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HYDROXYFASUDIL MONOHYDROCHLORIDE Eigenschaften
- Schmelzpunkt:
- >250 (dec.)
- storage temp.
- Inert atmosphere,2-8°C
- L?slichkeit
- H2O: >5mg/mL
- Aggregatzustand
- solid
- Farbe
- white
- Wasserl?slichkeit
- Soluble in water (20mM)
- InChIKey
- XWWFOUVDVJGNNG-UHFFFAOYSA-N
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher |
Xn |
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R-S?tze: |
22 |
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WGK Germany |
3 |
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Bildanzeige (GHS) |
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Alarmwort |
Warnung |
Gefahrenhinweise |
Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
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Sicherheit |
P264 |
Nach Gebrauch gründlich waschen. |
P264 |
Nach Gebrauch gründlich waschen. |
P270 |
Bei Gebrauch nicht essen, trinken oder rauchen. |
P301+P312 |
BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
P501 |
Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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HYDROXYFASUDIL MONOHYDROCHLORIDE Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R22:Gesundheitssch?dlich beim Verschlucken.
Chemische Eigenschaften
Off-White Solid
Allgemeine Beschreibung
A cell-permeable, hydroxylated metabolite of HA 1077 (Fasudil; Cat. No. 371970) that displays anti-anginal properties. Acts as an ATP-competitive and a reversible inhibitor of Rho-kinase (IC
50 = 0.9 and 1.8 μM using a peptide and MLC as substrate, respectively) with ~100-fold greater selectivity over MLCK, MRCKβ, and PKC. Reported to inhibit the Rho kinase-mediated contraction both
in vitro and
in vivo.
HYDROXYFASUDIL MONOHYDROCHLORIDE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
HYDROXYFASUDIL MONOHYDROCHLORIDE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 101)Lieferanten
155558-32-0()Verwandte Suche:
- 5-[(Hexahydro-1H-1,4-diazepin-1-yl)sulfonyl]-1(2H)-isoquinolinone
- Hydroxyfasudil Hydrochloride
- 1-(1-hydroxy-5-isoquinolinesulfonyl)homopiperazine monohydrochloride
- HYDROXYFASUDIL MONOHYDROCHLORIDE
- Hydroxyfasudil hydrochloride hydrate,1-(1-Hydroxy-5-isoquinolinesulfonyl)homopiperazine hydrochloride hydrate
- 1-(1-Hydroxy-5-isoquinolinesulfonyl)homopiperazine hydrochloride hydrate
- Hydroxyfasudil hydrochloride hydrate
- Hydroxyfasudil (HA-1100)
- HA-1100 HYDROCHLORIDE;HA 1100 HYDROCHLORIDE;HA1100 HYDROCHLORIDE
- 5-(1,4-diazepan-1-ylsulfonyl)-2h-isoquinolin-1-one
- Hydroxyfasudil hydrochloride (HA-1100 hydrochloride)
- Hydroxyfasudil - CAS 155558-32-0 - Calbiochem
- Hydroxyfasudil HCl
- Hydroxyfasudil (HA-1100) HCl
- 1(2H)-Isoquinolinone, 5-[(hexahydro-1H-1,4-diazepin-1-yl)sulfonyl]-, hydrochloride (1:1)
- Fasudil Impurity 7 HCl
- Fasudil Hydroxy
- 5-((1,4-diazepan-1-yl)sulfonyl)isoquinolin-1-ol hydrochloride
- 5-[(1,4-Diazepan-1-yl)sulfonyl]isoquinolin-1(2H)-one Hydrochloride
- Hydroxyfasudil HCl (HA1100)
- 5-(1,4-diazepan-1-ylsulfonyl)-2H-isoquinolin-1-one,hydrochloride
- HA-1100,ROCK,Hydroxyfasudil Hydrochloride,Hydroxyfasudil,Rho-associated kinase,HA 1100,inhibit,HA1100,Rho-kinase,Rho-associated protein kinase,ROK,Inhibitor
- Hydroxyfasudil hydrochloride hydrate Hydroxyfasudil hydrochloride
- HA 1100 hydrochloride (Hydroxyfasudil)
- 155558-32-0
- C14H17N3O3SHCl
- Various Metabolites and Impurities
- Intermediates & Fine Chemicals
- Metabolites & Impurities
- Pharmaceuticals