Thiocolchicin
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- CAS-Nr.
- 2730-71-4
- Bezeichnung:
- Thiocolchicin
- Englisch Name:
- thiocolchicine
- Synonyma:
- NSC 186301;thiocolchicine;thiocholchicine;10-Thiocolchicine;Thiocolchicoside EP Impurity B;10-Demethoxy-10-methylthiocolchicine;(S)-7-Acetylamino-6,7-dihydro-10-methylthio-1,2,3-trimethoxybenzo[a]heptalen-9(5H)-one;(S)-7α-Acetylamino-6,7-dihydro-10-(methylthio)-1,2,3-trimethoxybenzo[a]heptalene-9(5H)-one;N-[(S)-5,6,7,9-Tetrahydro-1,2,3-trimethoxy-10-methylthio-9-oxobenzo[a]heptalen-7-yl]acetamide;(S)-N-(1,2,3-trimethoxy-10-(methylthio)-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl)acetamide
- CBNumber:
- CB1926071
- Summenformel:
- C22H25NO5S
- Molgewicht:
- 415.5
- MOL-Datei:
- 2730-71-4.mol
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Thiocolchicin Eigenschaften
- Schmelzpunkt:
- 193℃
- alpha
- D20 -221°
- Siedepunkt:
- 729.1±60.0 °C(Predicted)
- Dichte
- 1.27±0.1 g/cm3(Predicted)
- storage temp.
- -20°C
- L?slichkeit
- DMSO: soluble10mg/mL, clear
- Aggregatzustand
- powder
- pka
- 14.75±0.40(Predicted)
- Farbe
- white to beige
Thiocolchicin Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
Bright Yellow Solid
Verwenden
A muscle relaxant.
Biochem/physiol Actions
Thiocolchicine is an antimitotic alkaloid and apoptosis inducer that inhibits tubulin polymerization and microtubule assembly.
Thiocolchicin Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Thiocolchicin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 73)Lieferanten
- thiocolchicine
- thiocholchicine
- (S)-7-Acetylamino-6,7-dihydro-10-methylthio-1,2,3-trimethoxybenzo[a]heptalen-9(5H)-one
- (S)-7α-Acetylamino-6,7-dihydro-10-(methylthio)-1,2,3-trimethoxybenzo[a]heptalene-9(5H)-one
- 10-Demethoxy-10-methylthiocolchicine
- 10-Thiocolchicine
- N-[(S)-5,6,7,9-Tetrahydro-1,2,3-trimethoxy-10-methylthio-9-oxobenzo[a]heptalen-7-yl]acetamide
- N-[(7S)-5,6,7,9-Tetrahydro-1,2,3-triMethoxy-10-(Methylthio)-9-oxobenzo[a]heptalen-7-yl]acetaMide
- NSC 186301
- (S)-N-(1,2,3-trimethoxy-10-(methylthio)-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl)acetamide
- Thiocolchicoside EP Impurity B
- Acetamide, N-[(7S)-5,6,7,9-tetrahydro-1,2,3-trimethoxy-10-(methylthio)-9-oxobenzo[a]heptalen-7-yl]-
- breast,LoVo/DX,MDR-positive,Microtubule/Tubulin,inhibit,MCF-7,leukemia,Colchicine,Apoptosis,BALB/3T3,cancer,A-549,LoVo,Thiocolchicine,Analogue,Inhibitor
- N-[(7S,12aRa)-1,2,3-trimethoxy-10-(methylsulfanyl)-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide (thiocolchicine)
- 2730-71-4
- Intermediates & Fine Chemicals
- Pharmaceuticals
