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2-Furancarboxamide, N-(4-hexylphenyl)-5-nitro-

2-Furancarboxamide, N-(4-hexylphenyl)-5-nitro- Struktur
2244881-69-2
CAS-Nr.
2244881-69-2
Englisch Name:
2-Furancarboxamide, N-(4-hexylphenyl)-5-nitro-
Synonyma:
STING-IN-3;C-171 STING inhibitor;N-(4-hexylphenyl)-5-nitrofuran-2-carboxamide;2-Furancarboxamide, N-(4-hexylphenyl)-5-nitro-;genes,inhibit,ERIS,TMEM173,mmSTING,Inhibitor,Stimulator of Interferon Genes,STING,MPYS,MITA,stimulator,hsSTING,STINGIN3,interferon,STING IN 3
CBNumber:
CB18396720
Summenformel:
C17H20N2O4
Molgewicht:
316.35
MOL-Datei:
2244881-69-2.mol

2-Furancarboxamide, N-(4-hexylphenyl)-5-nitro- Eigenschaften

Siedepunkt:
388.5±37.0 °C(Predicted)
Dichte
1.208±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
L?slichkeit
DMF: 25 mg/ml,DMSO: 25 mg/ml
Aggregatzustand
A crystalline solid
pka
11.89±0.70(Predicted)
Farbe
Light yellow to green yellow

Sicherheit

2-Furancarboxamide, N-(4-hexylphenyl)-5-nitro- Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

C-171 is an inhibitor of stimulator of interferon genes (STING). It binds to STING, inhibits its palmitoylation, and prevents the recruitment and phosphorylation of TBK1. It selectively reduces human and mouse STING-, but not RIG-I or TBK1-, mediated IFN-β reporter activity in HEK293 cells when used at concentrations ranging from 0.02 to 2 μM.

2-Furancarboxamide, N-(4-hexylphenyl)-5-nitro- Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

2-Furancarboxamide, N-(4-hexylphenyl)-5-nitro- Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 22)Lieferanten
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  • 2-Furancarboxamide, N-(4-hexylphenyl)-5-nitro-
  • C-171 STING inhibitor
  • STING-IN-3
  • genes,inhibit,ERIS,TMEM173,mmSTING,Inhibitor,Stimulator of Interferon Genes,STING,MPYS,MITA,stimulator,hsSTING,STINGIN3,interferon,STING IN 3
  • N-(4-hexylphenyl)-5-nitrofuran-2-carboxamide
  • 2244881-69-2
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