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(Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate

(Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate Struktur
2093243-16-2
CAS-Nr.
2093243-16-2
Englisch Name:
(Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate
Synonyma:
Nintedanib-013-Z;Nidanibu Impurity 8;Nintedanib impurities11;(Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate;Nintedanib impurity 12/Methyl (Z)-3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate;1H-Indole-6-carboxylic acid, 2,3-dihydro-3-(hydroxyphenylmethylene)-2-oxo-, methyl ester, (3Z)-
CBNumber:
CB14656048
Summenformel:
C17H13NO4
Molgewicht:
295.29
MOL-Datei:
2093243-16-2.mol

(Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate Eigenschaften

Schmelzpunkt:
>215°C (dec.)
Siedepunkt:
536.9±50.0 °C(Predicted)
Dichte
1.357±0.06 g/cm3(Predicted)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
L?slichkeit
DMSO (Slightly), Methanol (Slightly, Heated)
Aggregatzustand
Solid
pka
4.50±1.00(Predicted)
Farbe
Yellow to Dark Yellow

Sicherheit

(Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

(Z)-Methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate is a useful intermediate for the preparation of nintedanib esylate. Nintedanib is a drug for the treatment of idiopathic pulmonary fibrosis.

(Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

(Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 42)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
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Tianjin Derchemist Science & Technology Co., Ltd. 22-58627059 13920586291
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Nanjing XiZe Biotechnology CO., Ltd. 025-66023220 0086-15250997978
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2093243-16-2()Verwandte Suche:

  • (Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate
  • Nintedanib impurity 12/Methyl (Z)-3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate
  • Nintedanib-013-Z
  • Nidanibu Impurity 8
  • Nintedanib impurities11
  • 1H-Indole-6-carboxylic acid, 2,3-dihydro-3-(hydroxyphenylmethylene)-2-oxo-, methyl ester, (3Z)-
  • 2093243-16-2
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