OXINDOLE I Chemische Eigenschaften,Einsatz,Produktion Methoden

Enzyminhibitor

This indole derivative (FW = 210.24 g/mol), also known as oxindole I, is a potent and selective inhibitor of the vascular endothelial growth factor (VEGF) receptor protein-tyrosine kinase Flk-1 (i.e., fetal liver kinase-1), IC50 = 390 nM, but a weaker inhibitor of platelet-derived growth factor receptor (PDGFR) protein-tyrosine kinase, IC50 = 12 μM. In addition, it also inhibits certain cyclin-dependent kinases: cyclin D1/cdk4 enzyme (IC50 = 4.9 μM) > cyclin E/cdk2 (IC50 = 10 μM) and cyclin B/cdk1 (IC50 = 10.2 μM).

OXINDOLE I Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

OXINDOLE I Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Beijing Taize Jiaye Technology Development Co., Ltd.	--		CHINA	6050	58
Shanghai Yijie Biological Technology Co., Ltd.	--	SHYIJIEBIO@126.COM	CHINA	3510	58
Xiamen Huijia Biological Technology Co., Ltd.	--		CHINA	6973	58
Shanghai Haoran Biotechnology Co., Ltd.	--	470003480@QQ.COM	CHINA	6955	58
Absin Bioscience Inc.	--	chenjw@absin.cn	CHINA	6654	58
Beijing Taize Ruida Technology Co., Ltd.	--	taizeorder@163.com	CHINA	6536	58
Beijing Bi Orange Blue Biotechnology Co., Ltd.	--	bo49855987@163.com	CHINA	6827	58
Beijing Zhijie Fangyuan Technology Co., Ltd.	--	15810200961@163.com	CHINA	6984	58
Kanto Chemical Co., Inc.	--	reag-info@gms.kanto.co.jp	Japan	6756	74
EMD Biosciences, Inc.	--	technical@calbiochem.com	United States	6529	66

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• OXINDOLE I
• 3-(1H-PYRROL-2-YLMETHYLENE)-1,3-DIHYDROINDOL-2-ONE