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ISX 9

ISX 9 Struktur
832115-62-5
CAS-Nr.
832115-62-5
Englisch Name:
ISX 9
Synonyma:
ISX 9;CS-1582;Isoxazole 9;Isoxazole (ISX-9);ISX 9(Isoxazole 9);Isoxazole 9 (ISX-9) ;Neuronal Differentiation Inducer III;ISX-9;ISX 9;NEURONAL DIFFERENTIATION INDUCER III;N-Cyclopropyl-5-(2-thienyl)-3-isoxazolecarboxamide;3-IsoxazolecarboxaMide, N-cyclopropyl-5-(2-thienyl)-
CBNumber:
CB12574687
Summenformel:
C11H10N2O2S
Molgewicht:
234.27
MOL-Datei:
832115-62-5.mol

ISX 9 Eigenschaften

Siedepunkt:
468.1±35.0 °C(Predicted)
Dichte
1.39±0.1 g/cm3(Predicted)
storage temp. 
-20°
L?slichkeit
Soluble in DMSO (up to 60 mg/ml) or in Ethanol (up to 16 mg/ml).
pka
13.60±0.20(Predicted)
Aggregatzustand
solid
Farbe
Tan
Stabilit?t:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitssch?dlich bei Verschlucken. Akute Toxizit?t oral Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P270, P301+P312, P330, P501
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.

ISX 9 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

N-Cyclopropyl-5-(thiophen-2-yl)isoxazole-3-carboxamide was shown to exhibit regulatory effects towards the expression of pH sensing G protein-coupled receptor-68 and is now a new drug target for ischemic heart disease.

Allgemeine Beschreibung

A cell-permeable isoxazole compound that selectively induces robust neuronal differentiation (Effective concentration = 20 μM) in various stem/progenitor cells. Induces insulin expression, and activates ERK signaling and histone acetylation in MIN6 pancreatic β cells. The underlying excitation-neurogenesis signaling is comprised of, at least in part, an initial NMDA receptor- and L-type chanenels-mediated Ca2+ influx, followed by an activation of CaMKII, phosphorylation/nuclear export of the MEF2 repressor HDAC5, the subsequent de-repression of MEF2, and the eventual activation of the HDAC-MEF2 epigenetic/transcriptional regulatory network.

ISX 9 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


ISX 9 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 127)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795
ivan@atkchemical.com China 32957 60
Alchem Pharmtech,Inc.
8485655694
sales@alchempharmtech.com United States 63687 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 32161 58
Career Henan Chemica Co
+86-0371-86658258 +8613203830695
laboratory@coreychem.com China 30239 58
Chemia Biotechnology(Shanghai) Co., Ltd
+8613816753574
info@chemia-pharm.com CHINA 311 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471
sales@sarms4muscle.com China 10473 58
InvivoChem
+1-708-310-1919 +1-13798911105
sales@invivochem.cn United States 6391 58
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd
+8618829768577
gao490372054@gamil.com China 1249 58
Nantong HI-FUTURE Biology Co., Ltd.
+undefined18051384581
sales@chemhifuture.com China 3135 58
ShenZhen Trendseen Biological Technology Co.,Ltd.
13417589054
trendseenbio@gmail.com China 11681 58

  • ISX 9
  • 3-IsoxazolecarboxaMide, N-cyclopropyl-5-(2-thienyl)-
  • N-Cyclopropyl-5-(thiophen-2-yl)isoxazole-3-carboxaMide
  • Neuronal Differentiation Inducer III
  • Isoxazole (ISX-9)
  • Isoxazole 9
  • Isoxazole 9 (ISX-9)
  • ISX 9(Isoxazole 9)
  • N-Cyclopropyl-5-(2-thienyl)-1,2-oxazole-3-carboxamide
  • CS-1582
  • N-Cyclopropyl-5-(2-thienyl)-3-isoxazolecarboxamide
  • ISX-9;ISX 9;NEURONAL DIFFERENTIATION INDUCER III
  • 832115-62-5
  • Inhibitors
  • Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
  • API
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