(1R,20'S)-20'-Dimethylamino-2-methylspiro[1H-isoindole-1,3'-[5α]pregnan]-3(2H)-one Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
This is the major alkaloid isolated from the leaves of Pachysandra terminalis
Sieb. et Zucc and occurs in the weakly basic fraction of the alkaloidal extract. It
is dextrorotatory with [α]
D + 35° (CHCI3). With LiAIH4 it yields the deoxo
derivative, m.p. 175-7°C; [α]
D + 35° which may be oxidized with manganese
dioxide in CHCl3 to give a compound C29H420N2, m.p. 273-6°C; [0']0 + 36°.
Einzelnachweise
Kikuchi et at., Tetrahedron Lett., 2077 (1968)
Kikuchi, Nishinga., ibid, 2519 (1969)
(1R,20'S)-20'-Dimethylamino-2-methylspiro[1H-isoindole-1,3'-[5α]pregnan]-3(2H)-one Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte