N-(3-Oxotetradecanoyl)-L-homoserine lactone
|
|
|
- CAS-Nr.
- 177158-19-9
- Englisch Name:
- N-(3-Oxotetradecanoyl)-L-homoserine lactone
- Synonyma:
- 3OC14-HSL;3-oxo-C14-HSL;N-3-oxo-Myristoyl-L-Homoserine lactone;N-(3-Oxotetradecanoyl)-L-homoserine lactone;3-oxo-N-[(3S)-2-oxooxolan-3-yl]tetradecanamide;N-3-oxo-tetradecanoyl-L-Homoserine lactone Exclusive;Tetradecanamide, 3-oxo-N-[(3S)-tetrahydro-2-oxo-3-furanyl]-
- CBNumber:
- CB12094820
- Summenformel:
- C18H31NO4
- Molgewicht:
- 325.44
- MOL-Datei:
- 177158-19-9.mol
|
N-(3-Oxotetradecanoyl)-L-homoserine lactone Eigenschaften
- Schmelzpunkt:
- 96-97 °C(Solv: ethyl acetate (141-78-6))
- Siedepunkt:
- 537.3±50.0 °C(Predicted)
- Dichte
- 1.04±0.1 g/cm3(Predicted)
- storage temp.
- −20°C
- L?slichkeit
- DMF: 20 mg/ml; DMSO: 20 mg/ml
- Aggregatzustand
- A crystalline solid
- pka
- 11.21±0.46(Predicted)
- Farbe
- White to off-white
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
|
| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
|
| Sicherheit |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
|
N-(3-Oxotetradecanoyl)-L-homoserine lactone Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. Controlling bacterial infections by quenching their quorum sensing systems is a promising field of study. The expression of specific target genes, such as transcriptional regulators belonging to the LuxIR family of proteins, is coordinated by the synthesis of diffusible acylhomoserine lactone (AHL) molecules. N-3-oxo-tetradecanoyl-L-homoserine lactone (3-oxo-C14-HSL) is a small diffusible signaling molecule involved in quorum sensing, thereby controlling gene expression and affecting cellular metabolism in bacteria. It appears later than shorter acyl chain AHLs in developing biofilms and, like other long chain 3-oxo-AHLs, stimulates the production of putisolvin, which in turn, inhibits biofilm formation.
Biochem/physiol Actions
N-(3-Oxotetradecanoyl)-L-homoserine lactone (3-oxo-C14-HSL) is among a group of homoserine lactones that includes N-octanoyl-homoserine lactone (N-C8-HSL), N-(3-oxodecanoyl) homoserine-L-lactone (3-oxo-C10 HSL), N-(3-oxododecanoyl)homoserine-L-lactone (3-oxo-C12-HSL), N-(3-hydroxydecanoyl)-L-homoserine lactone, and N-(3-hydroxyoctanoyl)-L-homoserine lactone involved in the processes of bacterial quorum sensing. These homoserine lactones are used to study the processes and mechanisms of bacterial quorum sensing.
N-(3-Oxotetradecanoyl)-L-homoserine lactone Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
N-(3-Oxotetradecanoyl)-L-homoserine lactone Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 32)Lieferanten
- N-(3-Oxotetradecanoyl)-L-homoserine lactone
- 3-oxo-N-[(3S)-2-oxooxolan-3-yl]tetradecanamide
- 3OC14-HSL
- 3-oxo-C14-HSL
- N-3-oxo-Myristoyl-L-Homoserine lactone
- N-3-oxo-tetradecanoyl-L-Homoserine lactone Exclusive
- Tetradecanamide, 3-oxo-N-[(3S)-tetrahydro-2-oxo-3-furanyl]-
- 177158-19-9
- Amino Acids
- Modified Amino Acids
- Quorum Sensing / Signaling Compounds
- Homoserine LactonesMicrobiology
