PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH
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- CAS-Nr.
- 217082-60-5
- Englisch Name:
- PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH
- Synonyma:
- Pyr-apelin-13;[PYR1]-APELIN-13;(Glp1)-Apelin-13;[pGlu1]-Apelin-13;{Glp}-RPRLSHKGPMPF;PYR-RPRLSHKGPMPF-OH;3-Dimethyluric acid;[PE]APELIN-13, HUMAN, BOVINE;(GLP1)-APELIN-13, HUMAN, BOVINE;(PYR1)-APELIN-13 (HUMAN, BOVINE)
- CBNumber:
- CB1113712
- Summenformel:
- C69H108N22O16S
- Molgewicht:
- 1533.8
- MOL-Datei:
- 217082-60-5.mol
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PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH Eigenschaften
- Dichte
- 1.51±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Store in freezer, under -20°C
- Aggregatzustand
- Powder
- pka
- 3.56±0.10(Predicted)
- Farbe
- White to off-white
- Wasserl?slichkeit
- Soluble to 1 mg/ml in sterile water
- Sequenz
- Pyr-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
Bildanzeige (GHS) |
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Alarmwort |
Warnung |
Gefahrenhinweise |
Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
src="/GHS07.jpg" width="20" height="20" /> |
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Sicherheit |
P261 |
Einatmen von Staub vermeiden. |
P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
The apelin gene encodes a pre-proprotein that is processed to generate bioactive peptides consisting of 36, 17, or 13 amino acids: apelin-36 , apelin-17, and apelin-13 , respectively. Apelin-13 is an endogenous ligand of the APJ receptor, activating this G protein-coupled receptor with an EC50 value of 0.37 nM. (Glp1)-Apelin-13 is a pyroglutamylated form of apelin-13, in that the N-terminal glutamine residue is cyclized to pyroglutamic acid. Like apelin-13, this compound is a potent APJ receptor agonist (EC50 = 0.30 nM). (Glp1)-Apelin-13 is the major apelin isoform in the plasma of healthy human subjects. It can have vasoconstrictor and antipyretic effects in vitro and in vivo.
PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 126)Lieferanten
- (GLP1)-APELIN-13, HUMAN, BOVINE
- GLP-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE
- (Glp1)-Apelin-13
- 5-Oxo-L-prolyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-seryl-L-histidyl-L-lysylglycyl-L-prolyl-L-methionyl-L-prolyl-L-phenylalanine
- Pyr-apelin-13
- GLP-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE: GRPRLSHKGPMPF
- [PE]APELIN-13, HUMAN, BOVINE
- PYR-RPRLSHKGPMPF-OH
- PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE
- PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH
- [PYR1]-APELIN-13
- (PYR1)-APELIN-13 (HUMAN, BOVINE)
- (PYR1)-APELIN-13 (HUMAN, BOVINE, MOUSE, RAT)
- [PGLU1]APELIN (24-36), HUMAN, BOVINE
- PGLU-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE
- 3-Dimethyluric acid
- PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH USP/EP/BP
- L-Phenylalanine, 5-oxo-L-prolyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-seryl-L-histidyl-L-lysylglycyl-L-prolyl-L-methionyl-L-prolyl-
- [pGlu1]-Apelin-13
- [Pyr1]-Apelin-13,XRPRLSHKGPMPF,[pGlu1]-Apelin-13, >98%
- (Pyr?)-Apelin-13 (human, bovine, mouse, rat) acetate salt
- [Pyr1]-Apelin-13 trifluoroacetate salt
- {Glp}-RPRLSHKGPMPF
- 217082-60-5
- C69H108N22O16S
- peptide