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Ergoline-8-methanol, 10-methoxy-1,6-dimethyl-, 8-(5-bromo-3-pyridinecarboxylate), (8α)-

Ergoline-8-methanol, 10-methoxy-1,6-dimethyl-, 8-(5-bromo-3-pyridinecarboxylate), (8α)- Struktur
58001-19-7
CAS-Nr.
58001-19-7
Englisch Name:
Ergoline-8-methanol, 10-methoxy-1,6-dimethyl-, 8-(5-bromo-3-pyridinecarboxylate), (8α)-
Synonyma:
Isoergoline;Isonicergoline;Nicergoline EP Impurity F(RSS);Ergoline-8-methanol, 10-methoxy-1,6-dimethyl-, 8-(5-bromo-3-pyridinecarboxylate), (8α)-;((6aR,9S,10aS)-10a-methoxy-4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)methyl 5-bromonicotinate;(6aR,9S,10aS)-10a-methoxy-4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl]methyl 5-bromopyridine-3-carboxylate (isonicergoline)
CBNumber:
CB08806413
Summenformel:
C24H26BrN3O3
Molgewicht:
484.39
MOL-Datei:
58001-19-7.mol

Ergoline-8-methanol, 10-methoxy-1,6-dimethyl-, 8-(5-bromo-3-pyridinecarboxylate), (8α)- Eigenschaften

Siedepunkt:
594.4±50.0 °C(Predicted)
Dichte
1.47±0.1 g/cm3(Predicted)
pka
6.33±0.40(Predicted)

Sicherheit

Ergoline-8-methanol, 10-methoxy-1,6-dimethyl-, 8-(5-bromo-3-pyridinecarboxylate), (8α)- Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

8-epi Nicergoline is an impurity of Nicergoline (N394550) which is a drug used for age-dependent cognitive impairment such as Alzheimers disease and other types of dementia. Nicergoline has shown to protect cultured neurons against β-amyloid toxicity. Nicergoline protects against neuronal cell death induced by activated microglia and astrocytes through the inhibition of inflammatory mediators and the upregulation of neurotrophic factors by glial cells. Nicergoline is a drug used for age-dependent cognitive impairment and it protects cultured neurons against β-amyloid toxicity.

Ergoline-8-methanol, 10-methoxy-1,6-dimethyl-, 8-(5-bromo-3-pyridinecarboxylate), (8α)- Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Ergoline-8-methanol, 10-methoxy-1,6-dimethyl-, 8-(5-bromo-3-pyridinecarboxylate), (8α)- Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 29)Lieferanten
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China National Standard Pharmaceutical Corporation Limited
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Moxin Chemicals
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QUALITY CONTROL SOLUTIONS LTD.
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Scinova Biotech(Guangzhou) Co., Ltd. 13268215580
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Heyuan broad spectrum Biotechnology Co., Ltd 0762-3393039 18023108599
2853058244@qq.com China 992 58
Shanghai Kewel Chemical Co., Ltd. 021-64609169 18901607656
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Yangzhou Changhua Biotechnology Co., Ltd. 13815846020; 13815846020
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SHENZHEN PHYSTANDARD BIO-TECH CO.,LTD 0755-0755-0755-83725350 13380397412
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Nanjing Shizhou Biology Technology Co.,Ltd 025-85560043 13675144456
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  • Ergoline-8-methanol, 10-methoxy-1,6-dimethyl-, 8-(5-bromo-3-pyridinecarboxylate), (8α)-
  • Isonicergoline
  • ((6aR,9S,10aS)-10a-methoxy-4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)methyl 5-bromonicotinate
  • (6aR,9S,10aS)-10a-methoxy-4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl]methyl 5-bromopyridine-3-carboxylate (isonicergoline)
  • Isoergoline
  • Nicergoline EP Impurity F(RSS)
  • 58001-19-7
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