5-Brom-1,10-phenanthrolin
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- CAS-Nr.
- 40000-20-2
- Bezeichnung:
- 5-Brom-1,10-phenanthrolin
- Englisch Name:
- 5-bromo-1,10-phenanthroline
- Synonyma:
- FFC;5-Bromo-1,1-phenanthroline;5-bromo-1,10-phenanthroline;1,10-Phenanthroline, 5-broMo-;N-phenyl-1,10-phenanthrolin-5-amine;5-bromo-1,10-phenanthroline 40000-20-2 CAS NO.40000-20-2
- CBNumber:
- CB0878034
- Summenformel:
- C12H7BrN2
- Molgewicht:
- 259.1
- MOL-Datei:
- 40000-20-2.mol
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5-Brom-1,10-phenanthrolin Eigenschaften
- Schmelzpunkt:
- 119°C(lit.)
- Siedepunkt:
- 417.6±25.0 °C(Predicted)
- Dichte
- 1.616
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- Aggregatzustand
- powder to crystal
- pka
- 3.98±0.10(Predicted)
- Farbe
- White to Light yellow to Light orange
- CAS Datenbank
- 40000-20-2
- EPA chemische Informationen
- 1,10-Phenanthroline, 5-bromo- (40000-20-2)
5-Brom-1,10-phenanthrolin Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
5-bromo-1,10-phenanthroline can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.
Synthese
The compound was synthesized using a modification of the preparation described by Mlochowski.35 The yield of product is quite sensitive to the amount of bromine employed, the temperature, and the reaction time. Higher temperatures result in the formation of varying amounts of 5,6-dibromophenanthroline and 1,10-phenanthroline-5,6-dione. In our hands, the following preparation resulted in the maximum yield of product. A 3.6 g (20 mmol) sample of phenanthroline was placed in a heavy-walled glass reaction tube with a Teflon screw top fitted with a Viton O-ring. The reaction vessel was placed in an ice bath, and 12 mL of oleum (15%) and 0.60 mL (11.6 mmol) of bromine were added. The reaction tube was placed in a silicon oil bath, and the temperature was slowly raised to 135 °C. After 23 h, the reaction mixture was cooled to room temperature, poured over ice, and neutralized with NH4OH. The mixture was extracted with CHCl3. The extracts were stirred with charcoal and then dried over Na2SO4. The crude reaction mixture contained about 5% unreacted phenanthroline as judged by 1H NMR spectroscopy. The solid was recrystallized from hot diethyl ether with a minimum amount of CH2Cl2. Yield 4.67 g (90%).
5-Brom-1,10-phenanthrolin Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
5-Brom-1,10-phenanthrolin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 124)Lieferanten
40000-20-2(5-Brom-1,10-phenanthrolin)Verwandte Suche:
- 5-bromo-1,10-phenanthroline
- 1,10-Phenanthroline, 5-broMo-
- FFC
- 5-Bromo-1,1-phenanthroline
- 5-bromo-1,10-phenanthroline 40000-20-2 CAS NO.40000-20-2
- N-phenyl-1,10-phenanthrolin-5-amine
- 40000-20-2
- 961685-26-3
- Electronic Chemicals
