6-Chloro-1-tetralone
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- CAS-Nr.
- 26673-31-4
- Englisch Name:
- 6-Chloro-1-tetralone
- Synonyma:
- 6-chloro-3,4-dihydronaphthalen-1(2H)-one;6-Chloro-3,4-dihydro-2H-naphthalen-1-one;6-chloro-3;5-CHLORO-1-INDOMONE;5-CHLORO-L-INDOMONE;6-Chloro-α-Tetralone;6-Chloro-1-tetralone;6-CHLORO-TETRAL-1-ON;6-Chloro-tetral-1-one;6-chlorotetralin-1-one
- CBNumber:
- CB0766902
- Summenformel:
- C10H9ClO
- Molgewicht:
- 180.63
- MOL-Datei:
- 26673-31-4.mol
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6-Chloro-1-tetralone Eigenschaften
- Schmelzpunkt:
- 53 °C
- Siedepunkt:
- 150°C/0.7mmHg(lit.)
- Dichte
- 1.248±0.06 g/cm3(Predicted)
- Brechungsindex
- 1.59
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- Aggregatzustand
- powder to lump
- Farbe
- White to Yellow to Orange
- CAS Datenbank
- 26673-31-4
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
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6-Chloro-1-tetralone Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
6-Chloro-1-tetralone is a novel and potent intermediate used for synthesis of pharmaceutical compounds.
Synthese
A solution of sodium nitrite (173 mg, 2.51 mmol) in water (5 mL) at 0 °C (ice-bath) was added to a
magnetically stirred suspension of 6-Amino-1-tetralone (360 mg, 2.23 mmol) in aqueous hydrochloric acid (10 mL, 6
M) at 0 °C. This reaction mixture was added dropwise to a solution of copper(I) chloride (267 mg,
2.70 mmol) in concentrated hydrochloric acid (5 mL) at 0 °C. It was allowed to warm up to room
100 temperature and stirred for a further 2 h after which it was neutralised with solid sodium carbonate,
extracted with ethyl acetate (3 × 20 mL) and concentrated in vacuo to give slightly yellow oil. This
material was subjected to flash chromatography (50% chloroform in hexane) and concentration of
the appropriate fractions afforded 6-chloro-1-tetralone (180 mg, 45%) as a waxy solid.
6-Chloro-1-tetralone Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
6-Chloro-1-tetralone Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 205)Lieferanten
26673-31-4()Verwandte Suche:
1-Chlornaphthalin
1-Chlor-2,3-epoxypropan
1,2,3,4-Tetrahydronaphthalin
Chlortalidon
Trazodon
2,6-Dimethyloct-7-en-2-ol
Chlormezanon
1,2,3,4-Tetrahydronaphthalin-2-on
Decahydronaphthalin
Nabumetone
1,2,3,4-Tetrahydro-1-naphthalinon
Chloressigs?ure
Chlordifluormethan
KETAMINE/ZYLAZINE SOLUTION--SCHEDULE*III ITEM
- 6-CHLORO-TETRAL-1-ON
- 6-Chloro-1-tetralone
- 6-Chloro-α-Tetralone
- 5-CHLORO-L-INDOMONE
- 6-Chloro-tetral-1-one
- 5-CHLORO-1-INDOMONE
- 3,4,6-trichloronaphthalen-1(2H)-one
- 6-chloro-3
- 1(2H)-Naphthalenone, 6-chloro-3,4-dihydro-
- 6-Chloro-1-tetralone 98%
- 6-chlorotetralin-1-one
- 6-Chloro-1-tetralone >
- 6-Chloro-3,4-dihydro-1(2H)-naphthalenone
- 6-Chloro-3,4-dihydro-2H-naphthalen-1-one
- 6-chloro-3,4-dihydronaphthalen-1(2H)-one
- 6-Chloro-3,4-dihydro-2H-1-naphthone
- 26673-31-4
- 11
