BERBERINE CHLORIDE
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- CAS-Nr.
- 141433-60-5
- Englisch Name:
- BERBERINE CHLORIDE
- Synonyma:
- BERBERINE HCL;BBR;BERBERIN HCL;5,6-DIHYDRO-9,10-DIMETHOXY-BENZO[G]-1,3-BENZODIOXOLO[5,6-A]QUINOLIZINIUM, CHLORIDE;Berberine chloride hydrate 97%;CI 75160;UMBELLATINE;BERBERINE CHLORIDE;TIMTEC-BB SBB006488;LABOTEST-BB LT00440956
- CBNumber:
- CB0758776
- Summenformel:
- C20H20ClNO5
- Molgewicht:
- 389.83
- MOL-Datei:
- 141433-60-5.mol
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BERBERINE CHLORIDE Eigenschaften
- Schmelzpunkt:
- 204-206 °C (dec.)
- storage temp.
- Sealed in dry,Room Temperature
- L?slichkeit
- DMSO (Slightly), Methanol (Slightly)
- Aggregatzustand
- Solid
- Colour Index
- 75160
- Farbe
- Pale Yellow to Yellow
- Wasserl?slichkeit
- Soluble in water.
- Sensitive
- Light Sensitive
- Merck
- 14,1154
- BRN
- 3836585
- Stabilit?t:
- Hygroscopic
- InChIKey
- VKJGBAJNNALVAV-UHFFFAOYSA-M
- CAS Datenbank
- 141433-60-5(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
Xn |
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| R-S?tze: |
20/21/22 |
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| WGK Germany |
2 |
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| RTECS-Nr. |
DR9866400 |
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| F |
3-10 |
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| TSCA |
Yes |
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| HS Code |
29399990 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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BERBERINE CHLORIDE Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Berberine chloride occurs together with Neprotine (q.v.) in Berberis insignis Hook, B.
umbellata Wall and Mahonia nepalensis DC. (Syn. Berberis nepalensis Spreng.).
It is optically inactive and crystallizes from H2O with 5.5 H2O. It yields crystal_x0002_line salts, e.g. the nitrate, m.p. 265-7°C (dec.); sulphate, m.p. 271-3°C (dec.)
and the picrate, m.p. 231°C (dec.). The base also furnishes a methyl ether, m.p.
265°C and on catalytic hydrogenation gives the tetrahydro derivative, m.p.
213-5°C (dec.). The ultraviolet spectrum resembles that of berberine (q.v.).
Oxidation with KMn04 in Me2CO gives hemipinic acid, identified as the
ethylimide, m.p. 90°C.
Verwenden
Berberine chloride is mainly used to treat gastroenteritis, dysentery and other intestinal infections, conjunctivitis and suppurative otitis media.
Allgemeine Beschreibung
Berberine chloride is an alkaloid with antibiotic properties. Berberine chloride induces reactive oxygen species (ROS) production and inhibits DNA topoisomerase. It has anti-tumor properties.
Einzelnachweise
Orekhov.,J. Amer. Pharm. Assoc., 30,247, (1941)
Chatterjee., ibid, 33,205,210 (1944)
BERBERINE CHLORIDE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
BERBERINE CHLORIDE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 299)Lieferanten
141433-60-5()Verwandte Suche:
- 5,6-Dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium chloride hydrate
- Berberine chloride hydrate, 97%, water <17%
- Berberine (berberine hydrochloride)
- 9,10-DiMethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-iuM chloride hydrate
- Berberine chloride hydrate technical, >=90% (AT)
- LABOTEST-BB LT00440956
- CI 75160
- BERBERINE HYDROCHLORIDE N-HYDRATE
- BERBERINE CHLORIDE
- 9,10-DIMETHOXY-5,6-DIHYDRO-[1,3]DIOXOLO[4,5-G]ISOQUINO[3,2-A]ISOQUINOLIN-7-YLIUM
- Berberine Hydrochloride、Berberine Sulphate
- UMBELLATINE
- NATURAL YELLOW 18 CHLORIDE
- TIMTEC-BB SBB006488
- Berberine chloride std.
- Berberin hydrochloride
- Berberine chloride hydrate, 13.18 % water
- Berberine Chloride n-Hydrate
- Berberine Chloride Hydrate>
- BERBERINE CHLORIDE HYDRATE 141433-60-5
- BERBERINE CHLORIDE USP/EP/BP
- 9,10-Dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium chloride dihydrate
- Berberine chloride, hydrate (technical) ≥90%
- TIANFU-CHEM BERBERINE CHLORIDE
- Berberine Chloride HyBerberine Chloride Hydratedrate
- Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium,5,6-dihydro-9,10-dimethoxy-, chloride, hydrate (1:1:)
- Berberine chloride hydrate 97%
- BERBERIN HCL
- BERBERINE HCL
- BBR
- 5,6-DIHYDRO-9,10-DIMETHOXY-BENZO[G]-1,3-BENZODIOXOLO[5,6-A]QUINOLIZINIUM, CHLORIDE
- Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium, 5,6-dihydro-9,10-dimethoxy-, chloride, hydrate (1:1:x)
- 5,6-dihydro-9,10-dimethoxy-Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium chloride hydrate (1:1:)
- 5,6-Dihydro-9,10-dimethoxy-benzogbenzod1,3dioxolo5,6-aquinolizinium chloride hydrate (1:1:)
- Berberine chloride hydrate, 13.18 % water in DMSO
- 141433-60-5
- C20H18NO4ClH2O
- C20H17NO4HCl
- BioChemical
- Antitumor Agents
- Anti-Proliferative Agents
- Cancer Research
- Isoquinoline Alkaloids
- Alkaloids
- Alkaloids
- Biochemistry
- Miscellaneous Natural Products
- Isoquinoline Alkaloids
