Dichlofluanid (in atembarer Form) Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R20:Gesundheitssch?dlich beim Einatmen.
R36:Reizt die Augen.
R43:Sensibilisierung durch Hautkontakt m?glich.
R50/53:Sehr giftig für Wasserorganismen, kann in Gew?ssern l?ngerfristig sch?dliche Wirkungen haben.
R20/21/22:Gesundheitssch?dlich beim Einatmen,Verschlucken und Berührung mit der Haut.
R11:Leichtentzündlich.
S-S?tze Betriebsanweisung:
S24:Berührung mit der Haut vermeiden.
S37:Geeignete Schutzhandschuhe tragen.
S60:Dieses Produkt und sein Beh?lter sind als gef?hrlicher Abfall zu entsorgen.
S61:Freisetzung in die Umwelt vermeiden. Besondere Anweisungen einholen/Sicherheitsdatenblatt zu Rate ziehen.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S16:Von Zündquellen fernhalten - Nicht rauchen.
Beschreibung
Dichlofluanid is solid sparingly soluble in
water, soluble in most organic solvents, and decomposes
in alkaline media.
Verwenden
Dichlofluanid is used to control a wide range of fungal diseases
including storage diseases on many crops.
Definition
ChEBI: A member of the class of sulfamides that is sulfamide in which the hydrogens attached to one of the nitrogens are replaced by methyl groups, while those attached to the other nitrogen are replaced by a phenyl and a [dichloro(fluoro)methyl]sulfanediyl group
A fungicide introduced in 1965 and used in the cultivation of fruit and vegetables, as well as in wood preservatives, it is no longer approved for use in the European Union.
Stoffwechselwegen
Dichlofluanid contains an unstable dichlorofluoromethylthio (sulfenyl)
moiety that has been shown to undergo rapid hydrolytic and metabolic
degradation to N',N'-dimethyl-N-phenylsulfamide (2) (dimethylsulfanilide).
By analogy with captan, presumably the dichlorofluoromethylthio
moiety can be transferred to the sulfur atoms of cellular thiols such as
cysteine and glutathione. Thus in the presence of thiols, dichlofluanid
is probably cleaved at the N-S bond to form thiophosgene (3) or
its monofluoro analogue and other gaseous products such as hydrogen
sulfide, hydrogen chloride and carbonyl sulfide. Thiophosgene or its
monofluoro analogue is rapidly hydrolysed by water. The dichlorofluoromethylthio
group and thiophosgene may be intermediates in the
formation of addition products such as thiazolidine-2-thione-4-carboxylic
acid (4) by addition to cysteine. A thiazolidine derivative of glutathione
may also be formed (5).
Dichlofluanid (in atembarer Form) Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
