4-Chloro-2-fluorobenzyl alcohol
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- CAS-Nr.
- 56456-49-6
- Englisch Name:
- 4-Chloro-2-fluorobenzyl alcohol
- Synonyma:
- (4-chloro-2-fluorophenyl)Methanol;RARECHEM AL BD 0387;4-CHLORO-2-FLUOROBENZYL ALCOHOL;(3,3'-DITHIOBISHYDROCINNAMIC ACID;Benzenemethanol, 4-chloro-2-fluoro-;4-Chloro-2-fluorobenzyl alcohol ISO 9001：2015 REACH
- CBNumber:
- CB0676047
- Summenformel:
- C7H6ClFO
- Molgewicht:
- 160.57
- MOL-Datei:
- 56456-49-6.mol
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4-Chloro-2-fluorobenzyl alcohol Eigenschaften
- Siedepunkt:
- 227.6±25.0 °C(Predicted)
- Dichte
- 1.344±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 13.68±0.10(Predicted)
- CAS Datenbank
- 56456-49-6(CAS DataBase Reference)
4-Chloro-2-fluorobenzyl alcohol Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
Synthese
A solution of 4-chloro-2-fluorobenzoic acid (300mg) in THF (15m1) was added at 0CLiAIH4 (130mg). The suspension was stirred at 0℃ for 16h. The reaction mixture was diluted with EA and aq. A solution of potassium sodium tartrate was stirred for lh at rt. The layers were separated, and the org. phasel was further washed with water. The combined org. layers were dried over MgSO4, filtrated off and evaporated in vacuo. The crude was purified by CC (Buechi Sepacore, 5g cartridge, solvent A: DCM, solvent B: 3N ammonia in MeOH, gradient in %B: 0 to 5, flow rate: 6.0 mI/mm) to afford 224mg of colourless oil 4-Chloro-2-fluorobenzyl alcohol. LCMS: (A) tR = 0.68 mm; [M+H]: not visible.
4-Chloro-2-fluorobenzyl alcohol Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
4-Chloro-2-fluorobenzyl alcohol Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 159)Lieferanten
56456-49-6()Verwandte Suche:
- RARECHEM AL BD 0387
- 4-CHLORO-2-FLUOROBENZYL ALCOHOL
- Benzenemethanol, 4-chloro-2-fluoro-
- 4-Chloro-2-fluorobenzyl alcohol ISO 9001：2015 REACH
- (4-chloro-2-fluorophenyl)Methanol
- (3,3'-DITHIOBISHYDROCINNAMIC ACID
- 56456-49-6
- 1576-61-7
- Alcohols
- Chlorine Compounds
- Fluorine Compounds
- Benzhydrols, Benzyl & Special Alcohols
