2-Hydroxy-4-(trifluoromethyl)quinoline
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- CAS-Nr.
- 25199-84-2
- Englisch Name:
- 2-Hydroxy-4-(trifluoromethyl)quinoline
- Synonyma:
- BUTTPARK 33\04-80;4-(Trifluoromethyl)quinolin-2-ol;4-Trifluoromethyl-1H-quinolin-2-one;4-trifluoroMethyl-2(1H)-quinolinone;4-(trifluoromethyl)quinolin-2(1H)-one;2-HYDROXY-4-(TRIFLUOROMETHYL)QUINOLINE;4--(TrifluoroMethyl)quinoline-2(H)-one;2-hydroxy-4-(trifluoroMethyl)quinqline;4-Trifluoromethyl-2(1H)-quinolinone,97%;2(1H)-Quinolinone, 4-(trifluoromethyl)-
- CBNumber:
- CB0496696
- Summenformel:
- C10H6F3NO
- Molgewicht:
- 213.16
- MOL-Datei:
- 25199-84-2.mol
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2-Hydroxy-4-(trifluoromethyl)quinoline Eigenschaften
- Schmelzpunkt:
- >240°C
- Siedepunkt:
- 284 ºC
- Dichte
- 1.391
- Flammpunkt:
- 126 ºC
- storage temp.
- Sealed in dry,Room Temperature
- Aggregatzustand
- Solid
- Farbe
- White
- InChI
- InChI=1S/C10H6F3NO/c11-10(12,13)7-5-9(15)14-8-4-2-1-3-6(7)8/h1-5H,(H,14,15)
- InChIKey
- UUROBWTVZZNDFD-UHFFFAOYSA-N
- SMILES
- N1C2=C(C=CC=C2)C(C(F)(F)F)=CC1=O
- CAS Datenbank
- 25199-84-2
2-Hydroxy-4-(trifluoromethyl)quinoline Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
White solid
Synthese
4-Trifluoromethylquinolin-2(1H)-one was prepared by reacting aniline and ethyl-4,4,4-trifluoroacetoacetate stirred in toluene.
Experimental Procedure: In a 1 L round flask fitted with a reflux condenser a mixture of 25.60 g aniline, 50.0 g ethyl-4,4,4-trifluoroacetoacetate 300 ml toluene was heated to reflux in an oil bath at 130 °C. After 20 min 3 ml water was added and the mixture was heated at reflux for another 24 h. the reaction mixture was cooled to room temperature and concentrated under reduced pressure. A round flask with 200 mL H2SO4 was heated to 80°C and the crude oil from the step before was added in portions to the H2SO4 keeping the internal temperature below 90°C, total addition time was approximately 40 min. After addition was complete, the mixture was stirred at 80°C for 1 h, cooled and poured onto 400 g crushed ice. The resulting solids were filtered, washed with water, and dried under vacuum at 40°C to give 33.0 g (50%) product (2-Hydroxy-4-(trifluoromethyl)quinoline) as a colorless solid.
2-Hydroxy-4-(trifluoromethyl)quinoline Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
2-Hydroxy-4-(trifluoromethyl)quinoline Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 117)Lieferanten
25199-84-2()Verwandte Suche:
α,α,α-Trifluor-3-tolualdehyd
α,α,α-Trifluor-p-toluidin
Chinhydron
2-Methylbenzotrifluoride
α,α,α-Trifluor-o-toluylsure
Trifluormethansulfonsaeure
3,6-Bis[(4-chlor-2-phosphonophenyl)azo]-4,5-dihydroxynaphthalin-2,7-disulfonsure
2-CHLOROTHIOPHENOL
α,α,α-Trifluor-p-kresol
2-Chinolon
4,5-Dichlor-2,3-dihydro-2-phenylpyridazin-3-on
4-Hydroxy-7-trifluormethylchinolin-3-carbonsure
4-Hydroxy-8-(trifluormethyl)chinolin-3-carbonsure
7-(Trifluorphenyl)chinolin-4-ol
8-(Trifluormethyl)chinolin-4-ol
Ethyl-4-hydroxy-8-(trifluormethyl)chinolin-3-carboxylat
2,8-Bis(trifluormethyl)chinolin-4-ol
Ethyl-4-hydroxy-7-trifluormethyl-3-chinolincarboxylat
- BUTTPARK 33\04-80
- 2-HYDROXY-4-(TRIFLUOROMETHYL)QUINOLINE
- 4-(Trifluoromethyl)quinolin-2-ol
- 4-Trifluoromethyl-1H-quinolin-2-one
- 2-Hydroxy-4-(trifluoromethyl)quinoline ,98%
- 4-(trifluoromethyl)quinolin-2(1H)-one
- 2-hydroxy-4-(trifluoroMethyl)quinqline
- 4--(TrifluoroMethyl)quinoline-2(H)-one
- 4-trifluoroMethyl-2(1H)-quinolinone
- 2(1H)-Quinolinone, 4-(trifluoromethyl)-
- 4-Trifluoromethyl-2(1H)-quinolinone,97%
- 2-HYDROXY-4-(TRIFLUOROMETHYL)QUINOLINE ISO 9001：2015 REACH
- 25199-84-2
- C10H6F3NO
