SWAINSONINE
CAS-Nr.
72741-87-8
Englisch Name:
SWAINSONINE
Synonyma:
8AR)-1;SwainMoia;Tridolgosir;SWAINSONINE;D-Swainsonine;(-)-Swainsonine;SWAINSONINE 98+%;(-)-D-Swainsonine;Swainsonine min. 99%;swainsonine synthetic
CBNumber:
CB0484750
Summenformel:
C8H15NO3
Molgewicht:
173.21
MOL-Datei:
72741-87-8.mol
SWAINSONINE Eigenschaften
Schmelzpunkt:
148-149°C
Siedepunkt:
353.3±21.0 °C(Predicted)
Dichte
1.38±0.1 g/cm3 (20 ºC 760 Torr)
storage temp.
-20°C
L?slichkeit
H2O: soluble1mg/mL
pka
14.01±0.60(Predicted)
Aggregatzustand
lyophilized powder
Farbe
white to faint yellow
Biologische Quelle
synthetic
Wasserl?slichkeit
Soluble to 50 mM in water
BRN
4175740
Stabilit?t:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO, ethanol or distilled water may be stored at -20°C for up to 3 months.
CAS Datenbank
72741-87-8
Sicherheit
Risiko- und Sicherheitserkl?rung
Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher
Xn
R-S?tze:
20/21/22
S-S?tze:
36
WGK Germany
3
RTECS-Nr.
NM2408666
HS Code
29339900
Bildanzeige (GHS)
Alarmwort
Warnung
Gefahrenhinweise
Code
Gefahrenhinweise
Gefahrenklasse
Abteilung
Alarmwort
Symbol
P-Code
H302
Gesundheitssch?dlich bei Verschlucken.
Akute Toxizit?t oral
Kategorie 4
Warnung
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P264, P270, P301+P312, P330, P501
H312
Gesundheitssch?dlich bei Hautkontakt.
Akute Toxizit?t dermal
Kategorie 4
Warnung
src="/GHS07.jpg" width="20" height="20" />
P280,P302+P352, P312, P322, P363,P501
H332
Gesundheitssch?dlich bei Einatmen.
Akute Toxizit?t inhalativ
Kategorie 4
Warnung
src="/GHS07.jpg" width="20" height="20" />
P261, P271, P304+P340, P312
Sicherheit
P280
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
SWAINSONINE Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R20/21/22:Gesundheitssch?dlich beim Einatmen,Verschlucken und Berührung mit der Haut.
S-S?tze Betriebsanweisung:
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
White Crystalline Solid
Occurrence
Swainsonia canescens yields this simple alkaloid.
Definition
ChEBI: An indolizidine alkaloid isolated from the plant Swainsona canescens with three hydroxy substituents at positions 1, 2 and 8.
Allgemeine Beschreibung
Swainsonine is produced by endophytes, plant and insect pathogens. It is synthesized from the pipecolic acid and mevalonic acid. Swainsonine is a water-soluble indole alkaloid.
Biologische Aktivit?t
Inhibitor of α -mannosidase II which inhibits glycoprotein processing. Displays anticancer and immune modulatory properties.
SWAINSONINE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
SWAINSONINE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 178)Lieferanten
Canada 1
China 134
Europe 1
Germany 3
India 1
Japan 2
New Zealand 1
Switzerland 2
United Kingdom 11
United States 22
Global 178
72741-87-8()Verwandte Suche:
6-Amino-8-(((aminocarbonyl)oxy)-methyl)-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino-(2',3': 3,4)pyrrolo(1,2-a)indol-4,7-dion,(1aS-(1a alpha, 8 beta, 8a alpha,8b alpha))-
1-Hexanol
Betain
Octacosan-1-ol
8-indolizinetriol,octahydro-,(1s,2r,8r,8ar)-2
(1S,2S,8R,8AR)-TRIHYDROXYINDOLIZIDINE
(1S,2R,8R,8AR)-1,2,8-OCTAHYDROINDOLIZIDINETRIOL
8ALPHA,BETA-INDOLIZIDINE-1,2ALPHA,8BETA-TRIOL
8ALPHA,BETA-INDOLIZIDINE-1ALPHA,2ALPHA,8BETA-TRIOL
8A-BETA-INDOLIZIDINE-1ALPHA,2ALPHA,8BETA-TRIOL
8A,B-INDOLIZIDINE-1,2A,8B-TRIOL
8A,B-OCTAHYDROINDOLIZIDINE-1A,2A,8B-TRIOL
swainsonine from locoweed
swainsonine from rhizoctonia*leguminicola
swainsonine synthetic
SWAINSONINE FROM METARRHIZIUM ANISOPLIAE
SWAINSONINE FROM RHIZOCTONIA &
SWAINSONINE 98+%
Tridolgosir
(-)-D-Swainsonine
(1S,2α,8β,8aβ)-Octahydro-1,2,8-indolizinetriol
(1S,8aβ)-Octahydroindolizine-1α,2α,8β-triol
D-Swainsonine
(1S,2R,8R,8aR)-Octahydro-1,2,8-indolizinetriol
SwainMoia
8a,-Octahydroindolizidine-1a,2a,8-triol
SWAINSONINE, SWAINSONA CANESCENS
8-indolizinetriol(1s-(1-alpha,2-alpha,8-beta,8a-beta))-octahydro-2
8-indolizinetriol,octahydro-,(1s-(1-alpha,2-alpha,8-beta,8a-beta))-2
(-)-SWAINSONINE
(1S,2R,8R,8AR)-1,2,8-OCTAHYDROINDOLIZIDINETRIOL
(1S,2S,8R,8AR)-TRIHYDROXYINDOLIZIDINE
8α,β-Octahydroindolizidine-1α,2α,8β-triol
(1S,2R,8R,8aR)-1,2,3,5,6,7,8,8a-Octahydroindolizine-1,2,8-triol
Swainsonine min. 99%
8AR)-1
SWAINSONINE FROM LOCOWEED, 500 UG*
SWAINSONINE
Swainsonine, Swainsona canescens - CAS 72741-87-8 - Calbiochem
1,2,8-Indolizinetriol,octahydro-, (1S,2R,8R,8aR)-
(-)-Swainsonine
Swainsonine, lysosomal alpha-mannosidase inhibitor
72741-87-8
Enzymes, Inhibitors, and Substrates
Enzyme Inhibitors by Type
Enzyme Inhibitors by Enzyme
Enzyme Inhibitors
L to O
Mannosidase, alpha-
Substrate Analogs
BioChemical
Biochemicals and Reagents
Antibiotics
Antibiotics N-S
Antibiotics A to Z
Alkaloids
Glycosidase Inhibitors
Inhibitors
Elisa Kit-plant ELISA Kit