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KEA1-97

KEA1-97 Struktur
2138882-71-8
CAS-Nr.
2138882-71-8
Englisch Name:
KEA1-97
Synonyma:
KEA1-97;KEA1-97 >=98% (HPLC);KEA1-97, 10 mM in DMSO;4,6-Dichloro-N-(4'-fluoro-[1,1'-biphenyl]-4-yl)-1,3,5-triazin-2-amine;4,6-Dichloro-N-(4'-fluoro-[1,1'-biphenyl]-4-yl)-1,3,5-triazin-2-amine;1,3,5-Triazin-2-amine, 4,6-dichloro-N-(4'-fluoro[1,1'-biphenyl]-4-yl)-;Apoptosis,KEA1 97,Proliferation,Apoptotic,Caspase,inhibit,KEA-1-97,DCTalkyne,KEA1-97,231MFP,Inhibitor,Selective,KEA197
CBNumber:
CB04668109
Summenformel:
C15H9Cl2FN4
Molgewicht:
335.16
MOL-Datei:
2138882-71-8.mol

KEA1-97 Eigenschaften

Siedepunkt:
530.3±52.0 °C(Predicted)
Dichte
1.466±0.06 g/cm3(Predicted)
storage temp. 
4°C, protect from light
L?slichkeit
DMSO : 100 mg/mL (298.36 mM; Need ultrasonic)
pka
0.57±0.10(Predicted)
Aggregatzustand
Solid
Farbe
White to light yellow

Sicherheit

KEA1-97 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

KEA1-97 is a Thioredoxin-Caspase 3 interaction disruptor. It was found to target lysine 72 of thioredoxin, inhibiting its interactions with caspase 3 and inducing apoptosis without affecting other thioredoxin activity. KEA1-97 induced apoptosis in breast cancer cells and treatment of immune-deficient SCID mice at 5 mg/kg ip impaired breast tumor xenograft growth.

KEA1-97 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

KEA1-97 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 33)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
ivan@atkchemical.com China 32965 60
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
Nantong HI-FUTURE Biology Co., Ltd. 		+undefined18051384581
 sales@chemhifuture.com China 3135 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38631 58
Aladdin Scientific 		+1-+1(833)-552-7181
sales@aladdinsci.com United States 57505 58
Shanghai SuperLan Chemcial Technique Centre 021-2022843681 15618226720
 lucy@atkchemical.com China 9987 58
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266
 China 4573 55
ShangHai Biochempartner Co.,Ltd 17754423994 17754423994
 2853530910@QQ.com China 8011 62
Shanghai Rechem science Co., Ltd. 21-31433387 15618786686
 sales@rechemscience.com China 2998 58
Shanghai Chaolan Chemical Technology Center 021-QQ：65489617 15618227136
 Sales@ATKchemical.com China 7312 58
  • KEA1-97
  • 1,3,5-Triazin-2-amine, 4,6-dichloro-N-(4'-fluoro[1,1'-biphenyl]-4-yl)-
  • KEA1-97 >=98% (HPLC)
  • 4,6-Dichloro-N-(4'-fluoro-[1,1'-biphenyl]-4-yl)-1,3,5-triazin-2-amine
  • Apoptosis,KEA1 97,Proliferation,Apoptotic,Caspase,inhibit,KEA-1-97,DCTalkyne,KEA1-97,231MFP,Inhibitor,Selective,KEA197
  • 4,6-Dichloro-N-(4'-fluoro-[1,1'-biphenyl]-4-yl)-1,3,5-triazin-2-amine
  • KEA1-97, 10 mM in DMSO
  • 2138882-71-8
  • C15H9Cl2FN4
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