Halcinonide Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

(–)-L-threo-PDMP is a ceramide analog and one of the four possible stereoisomers of PDMP . L-threo-PDMP is an enhancer of ganglioside biosynthesis. It increases glucosylceramide synthase activity by 4 and 8% when used at concentrations of 5 and 2.5 μM, respectively, in an enzyme assay. L-threo-PDMP increases the activity of ganglioside GM₃, GD₃, and GQ_1b synthases and increases the levels of glucosylceramide, lactosylceramide, and ganglioside GM₃ in B16 melanoma cells. It inhibits the growth of MCF-7, MDA-MB-468, SK-BR-3 cells with IC₅₀ values of 4, 7, and 6 μM, respectively. L-threo-PDMP increases neurite outgrowth and synapse formation in vitro and improves retention of a long-term memory learned prior to forebrain ischemia in rats when administered following ischemia at a dose of 40 mg/kg per day. The L-threo-PDMP isomer is the glucosylceramide synthetase stimulatory component of DL-threo-PDMP , while D-threo-PDMP is the inhibitory component. [Matreya, LLC. Catalog No. 1749]

Halcinonide Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Halcinonide Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6777	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11217	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24648	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	11974	58
SHANGHAI ZZBIO CO., LTD.	15102117276 19921389125	tech@zzbioco.com	China	12065	58

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• ()-L-threo-PDMP (hydrochloride)
• (?)-L-threo-PDMP hydrochloride
• (-)-L-threo-PDMP (hydrochloride)
• ()LthreoPDMP (hydrochloride),( ) L threo PDMP (hydrochloride)
• N-[(1S,2S)-2-hydroxy-1-(4-morpholinylmethyl)-2-phenylethyl]-decanamide, monohydrochloride
• 161491-04-9