ABD459 Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
ABD459 is a neutral antagonist of the central cannabinoid 1 (CB
1) receptor (K
i = 8.6 nM). It inhibits food consumption in nonfasted mice without affecting motor activity. ABD459 reduces active food seeking for 5-6 hours after treatment, with no rebound after washout. ABD459 also diminishes rapid eye movement (REM) sleep, with no alterations of wakefulness or non-REM sleep.
ABD459 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte