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(RS)-(TETRAZOL-5-YL)GLYCINE

(RS)-(TETRAZOL-5-YL)GLYCINE Struktur
138199-51-6
CAS-Nr.
138199-51-6
Englisch Name:
(RS)-(TETRAZOL-5-YL)GLYCINE
Synonyma:
C13738;LY 285265;Tet-glycine;Tetrazolyl Glycine;5-Tetrazolyl-glycine;(RS)-(Tetrazol-5-yl);(tetrazol-5-yl)glycine;L-(tetrazol-5-yl)glycine;(RS)-(TETRAZOL-5-YL)GLYCINE;aMino(2H-tetrazol-5-yl)acetic acid
CBNumber:
CB0429449
Summenformel:
C3H5N5O2
Molgewicht:
143.1
MOL-Datei:
138199-51-6.mol

(RS)-(TETRAZOL-5-YL)GLYCINE Eigenschaften

Siedepunkt:
447.1±55.0 °C(Predicted)
Dichte
1.804±0.06 g/cm3(Predicted)
storage temp. 
Store at RT
L?slichkeit
DMSO: 0.25mg/mL; PBS (pH 7.2): 0.2mg/mL
Aggregatzustand
Powder
pka
1.04±0.10(Predicted)
Wasserl?slichkeit
Soluble to 50 mM in water

Sicherheit

(RS)-(TETRAZOL-5-YL)GLYCINE Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Tetrazolyl glycine is an NMDA receptor agonist. It binds to rat brain membranes with IC50 values of 98 and 36 nM for [3H]CGS19755 and [3H]glutamate, respectively, in radioligand binding assays. It induces depolarization in rat cortical slices, an effect that is blocked by the NMDA receptor antagonist LY233053. It induces degeneration of GABAergic and cholinergic neurons in the striatum of adult rats and the formation of excitotoxic lesions and seizures in neonatal rats (ED50 = 0.071 mg/kg). Intrastriatal injection of tetrazolyl glycine (5 μM) increases COX-2 expression in striatal neurons and the vasculature near the striatal injection site in a mouse model of excitotoxicity-induced neuronal injury.

Verwenden

(RS)-(Tetrazol-5-yl)glycine is a highly potent NMDA receptor agonist demonstrating ~ 20X more activity than NMDA.

(RS)-(TETRAZOL-5-YL)GLYCINE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

(RS)-(TETRAZOL-5-YL)GLYCINE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 40)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
Shanxi Xuanran Import and Export Trade Co., Ltd. 		+8617735180244
 mike_yan@xuanranglobal.com CHINA 4017 58
Nextpeptide Inc 		+86-0571-81612335 +8613336028439
 sales@nextpeptide.com China 19908 58
LEAPCHEM CO., LTD. 		+86-852-30606658
market18@leapchem.com China 43340 58
Aladdin Scientific 		+1-+1(833)-552-7181
sales@aladdinsci.com United States 52924 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
 3bsc@sina.com China 15839 69
Sichuan Wei Keqi Biological Technology Co., Ltd. 028-81700200 18116577057
 3003855609@qq.com China 7787 56
EMMX Biotechnology LLC 888-539-0666
info@emmx.com United States 8447 60
Shanghai QianYan Bio-technology Co., Ltd 02781293128
orders@biochemsafebuy.com China 9923 55
Aikon International Limited 025-66113011 18112977050
 cb6@aikonchem.com China 15494 58

138199-51-6()Verwandte Suche:

  • (RS)-(TETRAZOL-5-YL)GLYCINE
  • (tetrazol-5-yl)glycine
  • 5-Tetrazolyl-glycine
  • C13738
  • Tet-glycine
  • aMino(2H-tetrazol-5-yl)acetic acid
  • Amino-(1H-tetrazol-5-yl)-acetic acid
  • 2H-Tetrazole-5-acetic acid, a-amino-
  • alpha-Amino-2H-tetrazole-5-acetic acid
  • LY 285265
  • 2H-Tetrazole-5-acetic acid, α-amino-
  • (RS)-(Tetrazol-5-yl)
  • 2-Amino-2-(2H-tetrazol-5-yl)acetic acid
  • Tetrazolyl Glycine
  • (RS)-(Tetrazol-5-yl)glycine/LY285265
  • L-(tetrazol-5-yl)glycine
  • Fos,iGluR,GluN2D,LY-285265,Ionotropic glutamate receptors,inhibit,Inhibitor,(RS)(Tetrazol5yl)glycine,GluN1,(RS) (Tetrazol 5 yl)glycine,GluN2A,LY285265,NMDA,seizure
  • 2H-Tetrazole-5-acetic acid, α-amino-
  • 138199-51-6
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