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ANGIOTENSIN II, HUMAN

ANGIOTENSIN II, HUMAN Struktur
4474-91-3
CAS-Nr.
4474-91-3
Englisch Name:
ANGIOTENSIN II, HUMAN
Synonyma:
ANGIOTENSIN II;Ang II;DRVYIHPF;TY-10721;AngiotensinⅡ;ANGIOTENSIN-2;H-DRVYIHPF-OH;angiotensin renin;ANTI-ANGIOTENSIN II;ile(5)-angiotensini
CBNumber:
CB0338057
Summenformel:
C50H71N13O12
Molgewicht:
1046.2
MOL-Datei:
4474-91-3.mol

ANGIOTENSIN II, HUMAN Eigenschaften

Siedepunkt:
809.08°C (rough estimate)
Dichte
1.1257 (rough estimate)
Brechungsindex
1.6700 (estimate)
RTECS-Nr.
BW2165000
storage temp. 
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
L?slichkeit
insoluble in DMSO; insoluble in EtOH; ≥100.2 mg/mL in H2O
Aggregatzustand
Powder
pka
pK1: 10.37 (25°C)
Farbe
orange
Wasserl?slichkeit
Soluble in Water (25 mg/ml), and 5% Acetic Acid (1 mg/ml).
Sequenz
H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-OH
Stabilit?t:
Hygroscopic
InChIKey
CZGUSIXMZVURDU-JZXHSEFVSA-N

Sicherheit

WGK Germany  3

ANGIOTENSIN II, HUMAN Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

It is known that tumor tissues including metastatic lymph nodes are composed of newly growing vessels which lack blood flow autoregulation and are influenced only secondarily by the responding somatic vessels. Human angiotensin II (AT II). a vasopressor, was introduced in Japan to improve the efficacy of systemic chemotherapy. In patients with various advanced cancers, i.v. infusion of AT II to achieve a mean blood pressure of 1.5 times of baseline (but not over 150 mm Hg) followed by a bolus injection of conventional cytotoxic agents increases blood flow 5-7 fold in tumor tissues and therefore, increases drug delivery to the target tissue resulting in enhanced chemotherapeutic effects. This induced-hypertension chemotherapy regimen can be performed safely with minimal side effects.

Verwenden

Cardiopulmonary resuscitation - not yet an approved application

Allgemeine Beschreibung

Functions in blood pressure maintenance. Stimulates the release of aldosterone from the adrenal gland. Has strong vasoconstrictive effects. Increases the entry of Ca2+ in heart muscle via voltage-sensitive channels and activates myosin light chain kinase. Activates JAK2 in smooth muscle cells. Activates p125FAK and a cytosolic 115-120 kDa calcium-dependent tyrosine kinase in rat epithelial cells. Also activates pp60c-src in vascular smooth muscle cells. Inhibits adenylate cyclase activity in spontaneously hypertensive rats.

ANGIOTENSIN II, HUMAN Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


ANGIOTENSIN II, HUMAN Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 245)Lieferanten
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4474-91-3()Verwandte Suche:


  • [ILE5]-ANGIOTENSIN 2
  • HYPERTENSION II HUMAN
  • L-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE
  • H-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-OH
  • FLUORESCEIN-NHCS-NH-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-OH
  • ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-OH 2CH3CHOOH H2O
  • ANGIOTENSIN II, HUMAN
  • ANGIOTENSIN II (HUMAN) ACOH 4H2O
  • ANGIOTENSIN II, [ASN1,VAL5]
  • ANGIOTENSIN II, DES-ASP1-[ILE8]
  • ANGIOTENSIN II - FLUORESCEIN RBIOPROBE(TM)
  • ANTI-ANGIOTENSIN II
  • ANTI-ANGIOTENSIN II, HUMAN
  • 5-l-isoleucine-angiotensini
  • 5-l-isoleucineangiotensinii
  • angiotensinii(mouse)
  • ile(5)-angiotensini
  • ANGIOTENSIN-2
  • H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-OH acetate salt
  • ProteoMassTM Angiotensin II MALDI-MS Standard
  • Angiotensin II-fluorescein human
  • ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE ACOH 4H2O
  • ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE
  • ANGIOTENSIN II, [SAR1,ALA8]
  • ANGIOTENSIN II, [SAR1,ILE8]
  • ANGIOTENSIN II, [SAR1,THR8]
  • Vals-hypertensin-II-Asp-β-amide
  • [Ile5]angiotensin II
  • Angiotensin II【guinea pig】
  • Angiotensin II【rabbit】
  • TY-10721
  • Angiotensin 2 (Human Type)
  • H-DRVYIHPF-OH
  • ANGIOTENSIN II, HUMA
  • HuMan angiotension Ⅱ Relative Molecular Weight
  • Angiotensin II, 5-L-isoleucine-
  • Angiotensin Acetate II
  • Angiotensin II, Ang II
  • ANGIOTENSIN II, HUMAN, OCTAPEPTIDE
  • ANGIOTENSIN II, [VAL5]
  • ProteoMass? Angiotensin II MALDI-MS Standard
  • ANGIOTENSIN 2; ANGIOTENSIN RENIN; ANGIOTENSIN RECEPTOR;
  • angiotensin renin
  • HYPERTENSIN II;ANG II
  • Angiotensin II trifluoroacetate salt H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-OH trifluoroacetate salt
  • Angiotensin II, Human - CAS 4474-91-3 - Calbiochem
  • ANGIOTENSIN II;HYPERTENSIN II;ANG II;DRVYIHPF
  • Angiotensin?II impurity
  • ANGIOTENSIN II, HUMAN USP/EP/BP
  • 4474-91-3 ANGIOTENSIN II, HUMAN
  • DRVYIHPF
  • Ang II
  • ANGIOTENSIN II
  • (2S,5S,8S,11S,14S,17S)-2-((1H-Imidazol-5-yl)methyl)-17-amino-5-((S)-sec-butyl)-1-((S)-2-(((S)-1-carboxy-2-phenylethyl)carbamoyl)pyrrolidin-1-yl)-14-(3-guanidinopropyl)-8-(4-hydroxybenzyl)-11-isopropyl-1,4,7,10,13,16-hexaoxo-3,6,9,12,15-pentaazanonadecan-19-oic acid
  • Angiotensin II human,Apoptosis,Angiotensin Receptor,Inhibitor,inhibit
  • Peptide Angiotensin 2 Andangiotensin II Human Acetate
  • AngiotensinⅡ
  • Angiotensin Ⅱ acetate
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