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FGF-401

FGF-401 Struktur
1708971-55-4
CAS-Nr.
1708971-55-4
Englisch Name:
FGF-401
Synonyma:
Roblitinib;0997;FGF-401;FGF 401;FGF-401;Roblitinib（FGF-401）;FGF401( Roblitinib);FGF-401 ISO 9001：2015 REACH;8-naphthyridine-1(2H)-carboxamide;N-[5-Cyano-4-[(2-methoxyethyl)amino]-2-pyridinyl]-7-formyl-3,4-dihydro-6-[(4-methyl-2-oxo-1-piperazinyl)methyl]-1,8-naphthyridine-1(2H)-carboxamide;N-[5-cyano-4-(2-methoxyethylamino)pyridin-2-yl]-7-formyl-6-[(4-methyl-2-oxopiperazin-1-yl)methyl]-3,4-dihydro-2~{H}-1,8-naphthyridine-1-carboxamide
CBNumber:
CB03166185
Summenformel:
C25H30N8O4
Molgewicht:
506.56
MOL-Datei:
1708971-55-4.mol

FGF-401 Eigenschaften

Siedepunkt:
852.1±65.0 °C(Predicted)
Dichte
1.39±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
L?slichkeit
DMSO:5.4(Max Conc. mg/mL);10.66(Max Conc. mM)
Chloroform:30.0(Max Conc. mg/mL);59.22(Max Conc. mM)
Aggregatzustand
A crystalline solid
pka
11.40±0.20(Predicted)
Farbe
White to off-white

Sicherheit

FGF-401 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

FGF401 is an inhibitor of FGF receptor 4 (FGFR4; IC50 = 1.9 nM). It inhibits proliferation of Huh7 carcinoma cells with an IC50 value of 12 nM. FGF401 induces bile acid synthesis in dogs, increasing plasma and fecal levels of bile acids when administered at a dose of 45 mg/kg per day for four weeks. It also decreases serum cholesterol when administered at doses ranging from 5 to 45 mg/kg per day.

FGF-401 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

FGF-401 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 108)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
ivan@atkchemical.com China 32820 60
Zhejiang ZETian Fine Chemicals Co. LTD 		+8618957127338
 stella@zetchem.com China 2136 58
BOC Sciences 		+1-631-485-4226
inquiry@bocsci.com United States 19553 58
career henan chemical co 		+86-0371-86658258 +8613203830695
 factory@coreychem.com China 29815 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 31991 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226
 sales@hzclap.com CHINA 6312 58
Dideu Industries Group Limited 		+86-29-89586680 +86-15129568250
 1026@dideu.com China 23325 58
Zhejiang J&C Biological Technology Co.,Limited 		+1-2135480471 +1-2135480471
 sales@sarms4muscle.com China 10473 58
CR Corporation Limited 		+8613062833949
 fred.wen@crcorporation.cn China 8647 58
InvivoChem 		+1-708-310-1919 +1-13798911105
 sales@invivochem.cn United States 6391 58
  • 8-naphthyridine-1(2H)-carboxamide
  • 0997
  • FGF-401
  • N-(5-cyano-4-((2-methoxyethyl)amino)pyridin-2-yl)-7-formyl-6-((4-methyl-2-oxopiperazin-1-yl)methyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxamide
  • N-[5-cyano-4-(2-methoxyethylamino)pyridin-2-yl]-7-formyl-6-[(4-methyl-2-oxopiperazin-1-yl)methyl]-3,4-dihydro-2~{H}-1,8-naphthyridine-1-carboxamide
  • Roblitinib（FGF-401）
  • FGF 401;FGF-401
  • N-[5-Cyano-4-[(2-methoxyethyl)amino]-2-pyridinyl]-7-formyl-3,4-dihydro-6-[(4-methyl-2-oxo-1-piperazinyl)methyl]-1,8-naphthyridine-1(2H)-carboxamide
  • 1,8-Naphthyridine-1(2H)-carboxamide, N-[5-cyano-4-(2-methoxyethyl)amino]-2-pyridinyl]-7-formyl-3,4-dihydro-6-[(4-methyl-2-oxo-1-piperazinyl)methyl]-
  • FGF401( Roblitinib)
  • FGF-401 ISO 9001：2015 REACH
  • Roblitinib
  • N-{5-cyano-4-[(2-methoxyethyl)amino]pyridin-2-yl}-7-formyl-6-[(4-methyl-2-oxopiperazin-1-yl)methyl]-1,2,3,4-tetrahydro-1,8-naphthyridine-1-carboxamide
  • 1708971-55-4
  • API
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