成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

Fenfluraminhydrochlorid

Fenfluramine hydrochloride Struktur
404-82-0
CAS-Nr.
404-82-0
Bezeichnung:
Fenfluraminhydrochlorid
Englisch Name:
Fenfluramine hydrochloride
Synonyma:
FENFLURAMINE HCL;ponderal;ponderax;FENFLURAMINE HYDROCHLORIDE;FEBFLURAMINE HYDROCHLORIDE;phenfluoraminehydrochloride;Fenfluramine HCl in Methanol;rac Fenfluramine Hydrochloride;2H6]-Fenfluramine hydrochloride;(+/-)-FENFLURAMINE HYDROCHLORIDE
CBNumber:
CB0314194
Summenformel:
C12H17ClF3N
Molgewicht:
267.72
MOL-Datei:
404-82-0.mol

Fenfluraminhydrochlorid Eigenschaften

Schmelzpunkt:
1660C
Siedepunkt:
108-112 °C(Press: 12 Torr)
storage temp. 
2-8°C
L?slichkeit
Chloroform (Slightly), DMSO (Slightly), Methanol (Sparingly)
Aggregatzustand
A solid
Stabilit?t:
Hygroscopic
CAS Datenbank
404-82-0(CAS DataBase Reference)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher T
R-S?tze: 25-23/24/25
S-S?tze: 7-16-36/37-45-36/37/39-22
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3
RTECS-Nr. DA0295500
HazardClass  6.1(b)
PackingGroup  III
Toxizit?t LD50 oral in rabbit: 50mg/kg
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Achtung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H300 Lebensgefahr bei Verschlucken. Akute Toxizit?t oral Kategorie 2 Achtung GHS hazard pictogramssrc="/GHS06.jpg" width="20" height="20" /> P264, P270, P301+P310, P321, P330,P405, P501
Sicherheit
P264 Nach Gebrauch gründlich waschen.
P264 Nach Gebrauch gründlich waschen.
P270 Bei Gebrauch nicht essen, trinken oder rauchen.
P301+P310 BEI VERSCHLUCKEN: Sofort GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen.
P321 Besondere Behandlung
P330 Mund ausspülen.
P405 Unter Verschluss aufbewahren.
P501 Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen.

Fenfluraminhydrochlorid Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R25:Giftig beim Verschlucken.

S-S?tze Betriebsanweisung:

S7:Beh?lter dicht geschlossen halten.
S16:Von Zündquellen fernhalten - Nicht rauchen.
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn m?glich, dieses Etikett vorzeigen).

Chemische Eigenschaften

Crystalline Solid

Verwenden

Controlled substance. Anorexic

Definition

ChEBI: The hydrochloride salt of fenfluramine. It binds to the serotonin reuptake pump, causing inhbition of serotonin uptake and release of serotonin. The resulting increased levels of serotonin lead to greater serotonin receptor activation which in turn lead to enhancement of serotoninergic transmission in the centres of feeding behavior located in the hypothalamus. This suppresses the appetite for carbohydrates. Fenfluramine hydrochloride was used for treatment of diabetes and obesity. It was withdrawn worldwide after reports of heart valve disease and pulmonary hypertension.

Allgemeine Beschreibung

Fenfluramine hydrochloride, (±)N-ethyl- -methyl-m-(trifluoromethyl)phenethylamine hydrochloride (Pondimin), isunique in this group of drugs, in that it tends to produce sedationrather than excitation. Effects are said to be mediatedprincipally by central serotoninergic, rather than central noradrenergic,mechanisms. In large doses in experimental animals,the drug is a serotonin neurotoxin.It was withdrawnfrom human use after reports of heart valve damage and pulmonaryhypertension. From its structure, more apolar or hydrophobiccharacter than amphetamine, tropism for serotoninergicneurons would be expected. Likewise, thestructure suggests an indirect mechanism. If an indirectmechanism were operative, then all postsynaptic 5-HT receptors could be activated. Evidence from several studies indicatesthat the 5-HT1B and the 5-HT2C receptors are mostresponsible for the satiety effects of 5-HT. 5-HT may alsoinfluence the type of food selected (e.g., lower-fat food intake).The(+) isomer, dexfenfluramine (Redux), has agreater tropism for 5-HT systems than the racemic mixture.It, too, was withdrawn because of toxicity.

Sicherheitsprofil

Poison by ingestion, intravenous, and intraperitoneal routes. Human systemic effects by ingestion: mydriasis, change in motor activity, nausea. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits very toxic fumes of F-, NOx, and HCl

Fenfluraminhydrochlorid Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

404-82-0(Fenfluraminhydrochlorid)Verwandte Suche:


  • FENFLURAMINE HYDROCHLORIDE MM(CRM STANDARD)
  • N-Ethyl-a-methyl-3-(trifluoromethyl)benzeneethanamine Hydrochloride
  • (+)-n-ethyl-α-methyl-m-[trifluoromethyl]phenethylamine hydrochloride
  • BenzeneethanaMine,N-ethyl-a-Methyl-3-(trifluoroMethyl)-,hydrochloride (1:1)
  • (+)-N-Ethyl-α-methyl-m-[trifluoromethyl]phenethylamine
  • n-ethyl-1-[3-(trifluoromethyl)phenyl]-propan-2-amine
  • N-ETHYL-ALPHA-METHYL-3-(TRIFLUOROMETHYL)PHENETHYLAMINE HYDROCHLORIDE
  • N-ETHYL-ALPHA-METHYL-M-(TRIFLUOROMETHYL)PHENETHYLAMINE HYDROCHLORIDE
  • N-Ethyl-α-methyl-3-[trifluoromethyl] benzeneethanamine hydrochloride
  • rac Fenfluramine Hydrochloride
  • 1-(3-trifluoromethylphenyl)-2-ethylaminopropanehydrochloride
  • n-ethyl-alpha-methyl-m-(trifluoromethyl)-phenethylaminhydrochloride
  • phenfluoraminehydrochloride
  • ponderal
  • ponderax
  • (+/-)-FENFLURAMINE HYDROCHLORIDE
  • FENFLURAMINE HYDROCHLORIDE
  • FEBFLURAMINE HYDROCHLORIDE
  • FENFLURAMINE (UNLABELED) 1.0 MG/ML IN METHANOL
  • 3-trifluoromethyl-N-Ethylamphetamine (hydrochloride)
  • Fenfluramine hydrochloride USP/EP/BP
  • FENFLURAMINE HCL
  • 2H6]-Fenfluramine hydrochloride
  • 3-trifluoromethyl-N-Ethylamphetamine (hydrochloride) (exempt preparation)
  • Fenfluramine HCl in Methanol
  • Fenfluramine HCl in Acetonitrile
  • 404-82-0
  • C12H17ClF3N
  • C12H16F3NHClC12H17ClF3N
  • C12H16F3NHCl
  • FA - FL
  • Analytical Chromatography Product Catalog
  • Alphabetic
  • Analytical Standards
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Amines
  • Aromatics
Copyright 2019 ? ChemicalBook. All rights reserved