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THZ1

THZ1 Struktur
1604810-83-4
CAS-Nr.
1604810-83-4
Englisch Name:
THZ1
Synonyma:
THZ1;CS-1233;CDK7 inhibitor;THZ1 free base;THZ1, CDK7 inhibitor;THZ-1;THZ 1;CDK7 INHIBITOR;CDK7 INHIBITOR; THZ-1; THZ 1;THZ1 HY-80013 GTPL8052 SCHEMBL14979765;(E)-N-(3-((5-Chloro-4-(1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)-4-(4-(dimethylamino)but-2-en;(E)-N-(3-((5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)-4-(4-(dimethylamino)but-2-enamido)benzamide
CBNumber:
CB02715672
Summenformel:
C31H28ClN7O2
Molgewicht:
566.05
MOL-Datei:
1604810-83-4.mol

THZ1 Eigenschaften

Dichte
1.379±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
L?slichkeit
≥28.3 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
Aggregatzustand
Powder
pka
12.94±0.70(Predicted)
Farbe
Off-white to yellow

Sicherheit

THZ1 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

THZ1 is a covalent cyclin-dependent kinases 7 (CDK7) inhibitor. It has the ability to target a remote cysteine residue located outside of the canonical kinase domain, providing a means of achieving selectivity for CDK7.

THZ1 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

THZ1 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 105)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
ivan@atkchemical.com China 32951 60
BOC Sciences 		+1-631-485-4226
inquiry@bocsci.com United States 19553 58
career henan chemical co 		+86-0371-86658258 +8613203830695
 factory@coreychem.com China 29811 58
Hubei Ipure Biology Co., Ltd 		+8613367258412
 ada@ipurechemical.com China 10319 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226
 sales@hzclap.com CHINA 6312 58
Chemia Biotechnology（Shanghai） Co., Ltd 		+8613816753574
 info@chemia-pharm.com CHINA 311 58
InvivoChem 		+1-708-310-1919 +1-13798911105
 sales@invivochem.cn United States 6391 58
Nantong HI-FUTURE Biology Co., Ltd. 		+undefined18051384581
 sales@chemhifuture.com China 3135 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38470 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 		13417589054
 trendseenbio@gmail.com China 11681 58
  • (E)-N-(3-((5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)-4-(4-(dimethylamino)but-2-enamido)benzamide THZ1
  • THZ1
  • N-[3-[[5-Chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-4-[[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]benzamide
  • (E)-N-(3-((5-Chloro-4-(1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)-4-(4-(dimethylamino)but-2-en
  • (E)-N-(3-((5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)-4-(4-(dimethylamino)but-2-enamido)benzamide
  • THZ-1;THZ 1;CDK7 INHIBITOR
  • THZ1 HY-80013 GTPL8052 SCHEMBL14979765
  • Benzamide, N-[3-[[5-chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-4-[[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]-
  • CS-1233
  • THZ1, CDK7 inhibitor
  • CDK7 inhibitor
  • CDK7 INHIBITOR; THZ-1; THZ 1
  • THZ1 free base
  • THZ1 ?N-{4-[5-Chloro-4-(1H-indol-3-yl)-pyrimidin-2-ylamino]-phenyl}-4-(4-dimethylamino-but-2-enoylamino)-benzamide
  • (E)-N-(3-((5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)-4-(4-(dimethylamino)but-2-enamido)benzamide hydrochloride
  • 1604810-83-4
  • 16048-83-4
  • C31H28ClN7O2
  • API
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