4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-L-phenylalanine
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- CAS-Nr.
- 623950-02-7
- Englisch Name:
- 4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-L-phenylalanine
- Synonyma:
- EOS-61912;Eluxadoline int1;Eluxadoline Intermediate 2;L-Phenylalanine propionic acid;4-(aminocarbonyl)-N-[(1,1-dimethylethoxy);4'-Carbamoyl N-Boc-2',6'-dimethyl-L-Phenylalanine;4-(Aminocarbonyl)-N-Boc-2,6-dimethyl-L-phenylalanine;4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimet...;(S)-2-(Boc-Amino)-3-(4-carbamoyl-2,6-dimethylphenyl)propanoic Acid;(S)-2-(N-BOC-amino)-3-(4-formamido-2,6-dimethylphenyl)propanoic acid
- CBNumber:
- CB02651374
- Summenformel:
- C17H24N2O5
- Molgewicht:
- 336.38
- MOL-Datei:
- 623950-02-7.mol
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4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-L-phenylalanine Eigenschaften
- Schmelzpunkt:
- >210℃
- Siedepunkt:
- 497.1±45.0 °C(Predicted)
- Dichte
- 1.201
- storage temp.
- 2-8°C
- pka
- 3.88±0.17(Predicted)
- Aggregatzustand
- Solid
- Farbe
- White to off-white
- InChI
- InChI=1S/C17H24N2O5/c1-9-6-11(14(18)20)7-10(2)12(9)8-13(15(21)22)19-16(23)24-17(3,4)5/h6-7,13H,8H2,1-5H3,(H2,18,20)(H,19,23)(H,21,22)/t13-/m0/s1
- InChIKey
- ZLUHLTMMROGKKD-ZDUSSCGKSA-N
- SMILES
- C(O)(=O)[C@H](CC1=C(C)C=C(C(N)=O)C=C1C)NC(OC(C)(C)C)=O
- CAS Datenbank
- 623950-02-7
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
Bildanzeige (GHS) |
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Alarmwort |
Warnung |
Gefahrenhinweise |
Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
H312 |
Gesundheitssch?dlich bei Hautkontakt. |
Akute Toxizit?t dermal |
Kategorie 4 |
Warnung |
src="/GHS07.jpg" width="20" height="20" /> |
P280,P302+P352, P312, P322, P363,P501 |
H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
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Sicherheit |
P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-L-phenylalanine Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-L-phenylalanine is a phenylalanine derivative. It is mainly used as a pharmaceutical intermediate component in the preparation of opioid modulators and eluxadoline.
Verwenden
4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-L-phenylalanine is an intermediate used to prepare potential Dual delta-opioid antagonist/μ-opioid agonist used in the treatment of diarrhea. Irritable bowel syndrome.
4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-L-phenylalanine Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-L-phenylalanine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 131)Lieferanten
- (2S)-3-(4-carbamoyl-2,6-dimethylphenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid
- L-Phenylalanine, 4-(aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-
- (2S)-2{[(tert-butoxy)carbonyl]amino}-3-(4-carbamoyl-2,6-dimethylphenyl)propanoic acid
- (S)-2-(N-BOC-amino)-3-(4-formamido-2,6-dimethylphenyl)propanoic acid
- (S)-2-(tert-butoxycarbonylaMino)-3-(4-carbaMoyl-2,6-diMethylphenyl)propanoic aci
- 4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-L-phenylalanine###NA
- 4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-L-phenylalanine
- (s)-2-(tert-butoxycarbonylaMino)-3-(4-carbaMoyl-2,6-diMethylphenyl)propanoic acid
- EOS-61912
- Eluxadoline Intermediate 2
- (S)-2-(Boc-Amino)-3-(4-carbamoyl-2,6-dimethylphenyl)propanoic Acid
- L-Phenylalanine propionic acid
- Eluxadoline: 4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-L-phenylalanine
- Eluxadoline int1
- (S,E)-2-((tert-butoxy(hydroxy)methylene)amino)-3-(4-carbamoyl-2,6-dimethylphenyl)propanoic acid
- 4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimet...
- 4-(aminocarbonyl)-N-[(1,1-dimethylethoxy)
- 4'-Carbamoyl N-Boc-2',6'-dimethyl-L-Phenylalanine
- 4-(Aminocarbonyl)-N-Boc-2,6-dimethyl-L-phenylalanine
- (S)-2-tert-Butoxycarbonylamino-3-(4-carbamoyl-2,6-dimethyl-phenyl)-propionic acid
- 623950-02-7