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Piperazindihydrochlorid

PIPERAZINE DIHYDROCHLORIDE Struktur
142-64-3
CAS-Nr.
142-64-3
Bezeichnung:
Piperazindihydrochlorid
Englisch Name:
PIPERAZINE DIHYDROCHLORIDE
Synonyma:
dowzenedhc;Piperazine 2HCl;dihydropipwormer;PIPERAZINE DI HCL;piperazinewormerpremix;Piperazine hydrate CRS;piperazinehydrochloride;Piperazinium Dichloride;PIPERAZINE DIHYDROCHLORIDE;Olaparib Impurity 10 DiHCl
CBNumber:
CB0264741
Summenformel:
C4H12Cl2N2
Molgewicht:
159.06
MOL-Datei:
142-64-3.mol

Piperazindihydrochlorid Eigenschaften

Schmelzpunkt:
320°C(dec.)(lit.)
Siedepunkt:
262.01°C (rough estimate)
Dichte
1.3011 (rough estimate)
Brechungsindex
1.6300 (estimate)
storage temp. 
Inert atmosphere,Room Temperature
L?slichkeit
Water
Aggregatzustand
White crystalline solid
Farbe
White to Off-White
InChI
InChI=1S/C4H10N2.2ClH/c1-2-6-4-3-5-1;;/h5-6H,1-4H2;2*1H
InChIKey
CVVIJWRCGSYCMB-UHFFFAOYSA-N
SMILES
C1NCCNC1.Cl.Cl
LogP
-1.171 (est)
CAS Datenbank
142-64-3(CAS DataBase Reference)
EPA chemische Informationen
Piperazine dihydrochloride (142-64-3)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xn
R-S?tze: 36/37/38-42/43
S-S?tze: 22-26-36/37
OEB B
OEL TWA: 5 mg/m3
RTECS-Nr. TL4025000
3-10
HS Code  2933599550
Giftige Stoffe Daten 142-64-3(Hazardous Substances Data)
Toxizit?t mouse,LD50,intraperitoneal,1970mg/kg (1970mg/kg),LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION,Japanese Journal of Pharmacology. Vol. 17, Pg. 475, 1967.
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Achtung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H334 Kann bei Einatmen Allergie, asthmaartige Symptome oder Atembeschwerden verursachen. Sensibilisierung der Atemwege Kategorie 1 Achtung GHS hazard pictogramssrc="/GHS08.jpg" width="20" height="20" /> P261, P285, P304+P341, P342+P311,P501
H412 Sch?dlich für Wasserorganismen, mit langfristiger Wirkung. Langfristig (chronisch) gew?ssergef?hrdend Kategorie 3 P273, P501
Sicherheit
P202 Vor Gebrauch alle Sicherheitshinweise lesen und verstehen.
P261 Einatmen von Staub vermeiden.
P273 Freisetzung in die Umwelt vermeiden.
P302+P352 BEI BERüHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckm??ig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.
P308+P313 BEI Exposition oder falls betroffen: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen.

Piperazindihydrochlorid Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R42/43:Sensibilisierung durch Einatmen und Hautkontakt m?glich.

S-S?tze Betriebsanweisung:

S22:Staub nicht einatmen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.

Verwenden

Piperazine Dihydrochloride is an anthelmintic agent used in the treatment of parasitic worms in animals.

Allgemeine Beschreibung

White to cream-colored needles or powder. Mp: 318-20°C (with decomposition).

Reaktivit?t anzeigen

PIPERAZINE DIHYDROCHLORIDE is incompatible with the following: Water, HEAT, flames, oxidizers. PIPERAZINE DIHYDROCHLORIDE absorbs moisture from air. PIPERAZINE DIHYDROCHLORIDE may create flammable condition upon contact with HEAT, FLAMES and OXIDIZERS.

Sicherheitsprofil

Moderately toxic by intraperitoneal route. Mildly toxic by ingestion. When heated to decomposition it emits very toxic fumes of NOx and HCl. Used in making fiber, pharmaceuticals, and insecticides. See also PIPERAZINE.

m?gliche Exposition

Agricultural chemical, Suspected reprotoxic hazard. Piperazine is used to manufacture anthelmintics, antifilarials, antihistamines, and tranquilizers; the dihydrochloride is used in the manufacture of fibers, pharmaceuticals and insecticides. They are used as an intermediate in the manufacture of, pesticides, rubber chemicals and fibers. Also, piperazine is widely available, effective, and safe when used on an occasional basis against ascaride infections. It is also considerably cheaper than other anthelminthic drugs. In some countries where ascariasis is not endemic and where piperazine was used predominantly for the treatment of pinworn, it has been withdrawn from use on the grounds that other effective drugs are now available. Clinical dosages occasionally induce transient neurological signs and, in some circumstances, the drug may generate small amounts of nitrosamine in the stomach, which at considerably greater dosage in experimental animals has been demonstrated to have a carcinogenic potential.

Carcinogenicity

Piperazine dihydrochloride is an irritant and sensitizer. Little information exists on the toxicology of piperazine dihydrochloride in humans or in animals. Acute human exposures to the dust have reportedly resulted in irritation to the eyes, mild to moderate skin burns, and sensitization. Exposure levels and duration were not available.

l?uterung methode

Crystallise the salt from aqueous EtOH and dry it at 110o. [Beilstein 23 III/IV 17, 23/1 V 30.]

Inkompatibilit?ten

Aqueous solution is a strong base. Violent reaction with strong oxidizers and dicyanofurazan. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides, nitrogen compounds, carbon tetrachloride. Attacks aluminum, copper, nickel, magnesium and zinc.

Piperazindihydrochlorid Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Piperazindihydrochlorid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 191)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652
info@fdachem.com China 20284 58
Hubei xin bonus chemical co. LTD
86-13657291602
linda@hubeijusheng.com CHINA 22963 58
Chongqing Chemdad Co., Ltd
+86-023-6139-8061 +86-86-13650506873
sales@chemdad.com China 39894 58
Alchem Pharmtech,Inc.
8485655694
sales@alchempharmtech.com United States 63687 58
career henan chemical co
+86-0371-86658258 +8613203830695
factory@coreychem.com China 29811 58
Chemsigma International Co., Ltd.
+86-18136843612 +86-19951791336
info@chemsigma.com China 1369 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250
1026@dideu.com China 22784 58
AFINE CHEMICALS LIMITED
+86-0571-85134551
sales@afinechem.com China 15352 58
Alfa Chemistry

info@alfa-chemistry.com United States 2344 58
Dayang Chem (Hangzhou) Co.,Ltd.
571-88938639 +8617705817739
info@dycnchem.com China 52849 58

142-64-3(Piperazindihydrochlorid)Verwandte Suche:


  • diethylenediaminedihydrochloride
  • dihydrochloridesaltofdiethylenediamine
  • dihydropipwormer
  • dowzenedhc
  • piperazinehydrochloride
  • piperazinewormerpremix
  • PIPERAZINE DIHYDROCHLORIDE
  • PIPERAZINE HYDROCHLORIDE HYDRATE
  • PIPERAZINE DI HCL
  • PiperidineHydrochloride>98%
  • Piperazine dihydrochloride (non-medicinal)
  • PIPERAZINEDIHYDROCHLORIDE,ULTRAPURE
  • Piperazine Dihydrochloride (200 mg)
  • Piperazine Dihydrochloride 
  • Piperazine, hydrochloride (1:2)
  • Piperazine-1,4-diium chloride
  • Olaparib Impurity 10 DiHCl
  • PiperazineDihydrochlorideMonohydrate>
  • Piperazine hydrate CRS
  • Piperazine dihydrochloride salt
  • Piperazinium Dichloride
  • PIPERAZINE DIHYDROCHLORIDE ISO 9001:2015 REACH
  • Piperazine Dihydrochloride (1541907)
  • Piperazine 2HCl
  • Trimetazidine EP Impurity G DiHCl
  • 142-64-3
  • C4H10N22HClH2O
  • Building Blocks
  • Piperazines
  • Heterocyclic Building Blocks
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