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FX-11

FX-11 Struktur
213971-34-7
CAS-Nr.
213971-34-7
Englisch Name:
FX-11
Synonyma:
DK664;FX-11;FX11,FX 11;LDHA Inhibitor FX11;FX-11 (LDHA inhibitor FX11);7-Benzyl-2,3-dihydroxy-6-methyl-4-propyl-1-naphthoic acid;7-benzyl-2,3-dihydroxy-6-methyl-4-propylnaphthalene-1-carboxylic acid;2,3-Dihydroxy-6-Methyl-7-(phenylMethyl)-4-propyl-1-naphthalenecarboxylic Acid;1-Naphthalenecarboxylic acid, 2,3-dihydroxy-6-methyl-7-(phenylmethyl)-4-propyl-
CBNumber:
CB02627892
Summenformel:
C22H22O4
Molgewicht:
350.41
MOL-Datei:
213971-34-7.mol

FX-11 Eigenschaften

Schmelzpunkt:
183-184 °C
Siedepunkt:
570.1±50.0 °C(Predicted)
Dichte
1.260±0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer, Under inert atmosphere
L?slichkeit
DMSO (Slightly), Methanol (Slightly)
Aggregatzustand
Solid
pka
3.70±0.40(Predicted)
Farbe
Light Grey to Light Brown
InChI
InChI=1S/C22H22O4/c1-3-7-16-17-10-13(2)15(11-14-8-5-4-6-9-14)12-18(17)19(22(25)26)21(24)20(16)23/h4-6,8-10,12,23-24H,3,7,11H2,1-2H3,(H,25,26)
InChIKey
LVPYVYFMCKYFCZ-UHFFFAOYSA-N
SMILES
C1(C(O)=O)=C2C(C=C(C)C(CC3=CC=CC=C3)=C2)=C(CCC)C(O)=C1O

Sicherheit

FX-11 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

FX-11 is an inhibitor of lactate dehydrogenase-A (LDH-A; Ki = 8 μM). It is selective for LDH-A over GAPDH (Ki = >300 μM). FX-11 increases oxygen consumption and the production of reactive oxygen species (ROS), as well as induces cell death in P493-6 lymphoblastoid cells. In vivo, FX-11 (42 μg/animal, i.p.) reduces tumor volume in a P493-6 mouse xenograft model. It also reduces tumor weight in a BxPC-3 mouse xenograft model when administered at a dose of 2 mg/kg.

FX-11 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

FX-11 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 45)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Hebei Yanxi Chemical Co., Ltd. 		+8617531190177
 peter@yan-xi.com China 5857 58
Shanghai Daken Advanced Materials Co.,Ltd 		+86-371-66670886
info@dakenam.com China 18781 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32080 58
InvivoChem 		+1-708-310-1919 +1-13798911105
 sales@invivochem.cn United States 6391 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207
 sales@molcore.com China 49734 58
Nantong HI-FUTURE Biology Co., Ltd. 		+undefined18051384581
 sales@chemhifuture.com China 3135 58
Shanghai Acmec Biochemical Technology Co., Ltd. 		+undefined18621343501
 product@acmec-e.com China 33338 58
Aladdin Scientific 		+1-+1(833)-552-7181
sales@aladdinsci.com United States 52925 58
Junwee Chemical co., Ltd. 		+86-571-85808636 +86-13958122542
 sales@junweechem.com China 821 58
Shanghai Zhuangming Biopharma Co., Ltd. 		+86-19189228086 +86-18858568638
 sales@zmsilane.com China 642 58
  • FX-11
  • 2,3-Dihydroxy-6-Methyl-7-(phenylMethyl)-4-propyl-1-naphthalenecarboxylic Acid
  • 7-benzyl-2,3-dihydroxy-6-methyl-4-propylnaphthalene-1-carboxylic acid
  • FX-11 (LDHA inhibitor FX11)
  • LDHA Inhibitor FX11
  • 1-Naphthalenecarboxylic acid, 2,3-dihydroxy-6-methyl-7-(phenylmethyl)-4-propyl-
  • DK664
  • FX11,FX 11
  • 7-Benzyl-2,3-dihydroxy-6-methyl-4-propyl-1-naphthoic acid
  • 213971-34-7
  • Aromatics, Miscellaneous Reagents, Pharmaceuticals, Intermediates & Fine Chemicals
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