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N-[1-[[(Cyanomethyl)amino]carbonyl]cyclohexyl]-4-[2-(4-methyl-1-piperazinyl)-4-thiazolyl]benzamide

N-[1-[[(Cyanomethyl)amino]carbonyl]cyclohexyl]-4-[2-(4-methyl-1-piperazinyl)-4-thiazolyl]benzamide Struktur
294623-49-7
CAS-Nr.
294623-49-7
Englisch Name:
N-[1-[[(Cyanomethyl)amino]carbonyl]cyclohexyl]-4-[2-(4-methyl-1-piperazinyl)-4-thiazolyl]benzamide
Synonyma:
L 006235;I-006,235;L-006235;L 006235;L006235;N-(1-((cyanomethyl)carbamoyl)cyclohexyl)-4-(2-(4-methylpiperazin-1-yl)thiazol-4-yl)benzamide;N-[1-(cyanomethylcarbamoyl)cyclohexyl]-4-[2-(4-methylpiperazin-1-yl)-1,3-thiazol-4-yl]benzamide;N-[1-[[(Cyanomethyl)amino]carbonyl]cyclohexyl]-4-[2-(4-methyl-1-piperazinyl)-4-thiazolyl]benzamide;Benzamide, N-[1-[[(cyanomethyl)amino]carbonyl]cyclohexyl]-4-[2-(4-methyl-1-piperazinyl)-4-thiazolyl]-;L-235,L-006235,collagen,bone,loss,L 235,resorption,L006235,Inhibitor,inhibit,degradation,Cathepsin,L235
CBNumber:
CB02518862
Summenformel:
C24H30N6O2S
Molgewicht:
466.6
MOL-Datei:
294623-49-7.mol

N-[1-[[(Cyanomethyl)amino]carbonyl]cyclohexyl]-4-[2-(4-methyl-1-piperazinyl)-4-thiazolyl]benzamide Eigenschaften

Dichte
1.31±0.1 g/cm3(Predicted)
storage temp. 
Store at +4°C
L?slichkeit
<46.66mg/ml in DMSO
Aggregatzustand
solid
pka
12.07±0.20(Predicted)
Farbe
White

Sicherheit

N-[1-[[(Cyanomethyl)amino]carbonyl]cyclohexyl]-4-[2-(4-methyl-1-piperazinyl)-4-thiazolyl]benzamide Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

L 006235 is a cathepsin K inhibitor, which displays greater than 4000-fold selectivity against the lysosomal/endosomal antitargets cathepsin B, L, and S.

N-[1-[[(Cyanomethyl)amino]carbonyl]cyclohexyl]-4-[2-(4-methyl-1-piperazinyl)-4-thiazolyl]benzamide Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

N-[1-[[(Cyanomethyl)amino]carbonyl]cyclohexyl]-4-[2-(4-methyl-1-piperazinyl)-4-thiazolyl]benzamide Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 46)Lieferanten
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  • I-006,235
  • L 006235
  • N-[1-[[(Cyanomethyl)amino]carbonyl]cyclohexyl]-4-[2-(4-methyl-1-piperazinyl)-4-thiazolyl]benzamide
  • N-[1-(cyanomethylcarbamoyl)cyclohexyl]-4-[2-(4-methylpiperazin-1-yl)-1,3-thiazol-4-yl]benzamide
  • L-006235;L 006235;L006235
  • N-(1-((cyanomethyl)carbamoyl)cyclohexyl)-4-(2-(4-methylpiperazin-1-yl)thiazol-4-yl)benzamide
  • Benzamide, N-[1-[[(cyanomethyl)amino]carbonyl]cyclohexyl]-4-[2-(4-methyl-1-piperazinyl)-4-thiazolyl]-
  • L-235,L-006235,collagen,bone,loss,L 235,resorption,L006235,Inhibitor,inhibit,degradation,Cathepsin,L235
  • 294623-49-7
  • C24H30N6O2S
  • Potent, reversible cathepsin K inhibitor
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