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2-Amino-6-methyl-4-propyl-1,2,4-triazolo[1,5-a]pyrimidin-5(4H)-on

2-Amino-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5-one Struktur
27277-00-5
CAS-Nr.
27277-00-5
Bezeichnung:
2-Amino-6-methyl-4-propyl-1,2,4-triazolo[1,5-a]pyrimidin-5(4H)-on
Englisch Name:
2-Amino-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5-one
Synonyma:
ICI 63197;PP-796 emetic;Triazolopyrimidinones;ICI 63,197 >=98% (HPLC);AMINOPROPYLTRIAZOLOPYRIMIDONE;2-AMINO-6-METHYL-4-PROPYL-4H-[1,2,4]TRIAZOLO-[1,5-;2-Amino-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5-one;2-Amio-6-methyl-4-propyl-4H-[1,2,4]triazolo[1,5-a]pyrimidin-...;2-azanyl-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5-one;2-AMINO-6-METHYL-4-PROPYL-[1,2,4]TRIAZOLO[1,5- AJPYRIMIDIN-5-ONE
CBNumber:
CB0191331
Summenformel:
C9H13N5O
Molgewicht:
207.23
MOL-Datei:
27277-00-5.mol

2-Amino-6-methyl-4-propyl-1,2,4-triazolo[1,5-a]pyrimidin-5(4H)-on Eigenschaften

Schmelzpunkt:
161.8-163 °C
Siedepunkt:
459.9±28.0 °C(Predicted)
Dichte
1.44±0.1 g/cm3(Predicted)
Dampfdruck
0.004Pa at 25℃
storage temp. 
2-8°C
L?slichkeit
DMSO: 13 mg/mL
Aggregatzustand
solid
pka
2.96±0.40(Predicted)
Farbe
white
Wasserl?slichkeit
5.7g/L at 20℃
InChIKey
UQDVRVNMIJAGRK-UHFFFAOYSA-N
LogP
0.49 at 20℃
CAS Datenbank
27277-00-5(CAS DataBase Reference)
EPA chemische Informationen
2-Amino-4,5-dihydro-6-methyl-4-propyl-s-triazolo-(1,5-a)-pyrimidin-5-one (27277-00-5)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
RIDADR  2811
WGK Germany  1
HazardClass  6.1(b)
PackingGroup  III
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Achtung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H412 Sch?dlich für Wasserorganismen, mit langfristiger Wirkung. Langfristig (chronisch) gew?ssergef?hrdend Kategorie 3 P273, P501
Sicherheit
P273 Freisetzung in die Umwelt vermeiden.
P501 Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen.

2-Amino-6-methyl-4-propyl-1,2,4-triazolo[1,5-a]pyrimidin-5(4H)-on Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

ICI 63197 is a specific cAMP phosphodiesterase (PDE) inhibitor. It is potent in anatagonizing reserpine-induced hypothermia. potent PDE4 inhibitor.

Biologische Aktivit?t

Potent phosphodiesterase (PDE) 4 inhibitor (IC 50 = 35 nM for inhibition of [ 3 H]-rolipram binding to rat brain). Antidepressant following systemic administration in vivo .

Biochem/physiol Actions

Phosphodiesterase IV (PDE 4) inhibitor

2-Amino-6-methyl-4-propyl-1,2,4-triazolo[1,5-a]pyrimidin-5(4H)-on Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

2-Amino-6-methyl-4-propyl-1,2,4-triazolo[1,5-a]pyrimidin-5(4H)-on Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 154)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Hubei Jusheng Technology Co.,Ltd. 		18871490254
linda@hubeijusheng.com CHINA 28172 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427
 sales@conier.com China 49374 58
career henan chemical co 		+86-0371-86658258 +8613203830695
 factory@coreychem.com China 29810 58
Zhengzhou Alfa Chemical Co.,Ltd 		+8618530059196
 sale04@alfachem.cn China 11864 58
SIMAGCHEM CORP 		+86-13806087780
 sale@simagchem.com China 17365 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418671 +8618949823763
 sales@tnjchem.com China 34563 58
ANHUI WITOP BIOTECH CO., LTD 		+8615255079626
 eric@witopchemical.com China 23541 58
Dideu Industries Group Limited 		+86-29-89586680 +86-15129568250
 1026@dideu.com China 22787 58
AFINE CHEMICALS LIMITED 		+86-0571-85134551
sales@afinechem.com China 15352 58

27277-00-5(2-Amino-6-methyl-4-propyl-1,2,4-triazolo[1,5-a]pyrimidin-5(4H)-on)Verwandte Suche:

  • 2-AMINO-6-METHYL-4-PROPYL-[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-5(4H)-ONE
  • 2-AMINO-6-METHYL-4-PROPYL-4H-[1,2,4] TRIAZOLE-[1,5-A] PYRIMIDINE-5-ONE
  • 2-AMINO-6-METHYL-4-PROPYL-4H-[1,2,4]TRIAZOLO-[1,5-A]PYRIMIDIN-5-ONE
  • 2-AMINO-6-METHYL-5-OXO-4-N-PROPYL-4,5-DIHYDRO-S-TRIAZOLE[1,5-A]PYRIMIDINE
  • ICI 63197
  • 2,4]triazolo[1,5-a]pyrimidin-5(4h)-one,2-amino-6-methyl-4-propyl-[
  • 2-Amio-6-methyl-4-propyl-4H-[1,2,4]triazolo[1,5-a]pyrimidin-5-one
  • 2-AMINO-6-METHYL-5-OXO-4-N-PROPYL-4,5-DIHYDRO-S-TRIAZOLE[1,5-α]PYRIMIDIN
  • AMINOPROPYLTRIAZOLOPYRIMIDONE
  • 2-AMINO-6-METHYL-4-PROPYL-4H-[1,2,4] TRIAZOLE-[1,5-A] PYRIMIDONE-5-ONE
  • PP796,2-Amino-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5-one
  • 1,2,4Triazolo1,5-apyrimidin-5(4H)-one, 2-amino-6-methyl-4-propyl-
  • 2-AMINO-6-METHYL-5-OXO-4-N-PROPYL-4,5-DIHYDRO-S-TRIAZOLE[1,5- A ] PYRIMIDIN
  • 2-AMINO-6-METHYL-4-PROPYL-4H-[1,2,4]TRIAZOLE-[1,5-ALPHA]PYRIMIDONE-5-ONE
  • 2-AMINO-4,5-DIHYDRO-6-METHYL-4-PROPYL-S-TRIAZOLO(1,5-ALPHA)PYRIMIDIN-5-ONE
  • 2-Amino-6-methyl-4-propyl-1,2,4-triazolo[1,5-a]pyrimidin-5(4H)-on
  • 2-Amino-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5-one
  • 2-AMINO-6-METHYL-5-OXO-4-N-PROPYL-4,5-DIHYDRO-S-TRIAZOLE[1,5-ALPHA]PYRIMIDIN
  • PP-796 emetic
  • 2-Amino-6-methyl-4-propyl-4,5-dihydro[1,2,4]triazolo[1,5-a]pyrimidin-5-one
  • 2-azanyl-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5-one
  • ICI 63,197,2-Amino-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5(4H)-one
  • 2-aMino-6-Methyl-4-propyl-4H,5H-[1,2,4]triazolo[1,5-a]pyriMidin-5-one
  • 2-Amio-6-methyl-4-propyl-4H-[1,2,4]triazolo[1,5-a]pyrimidin-...
  • 2-AMINO-6-METHYL-4-PROPYL-4H-[1,2,4]TRIAZOLO-[1,5-
  • 2-Amino-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5-one USP/EP/BP
  • ICI 63,197 >=98% (HPLC)
  • 2-Amino-6-methyl-4-propyl-1,2,4-triazolo(1,5-a)pyrimidin-5(4H)-one 2-Amino-6-methyl-5-oxo-4n-propyl-4,5-dihydro-s-triazolo(1,5-a)pyrimidine 2-Amino-4,5-dihydro-6-methyl-4-propyl-5-triazolo-(1,5-c)-pyramidin-5-one 2-Amino-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5-one
  • 2-Amino-4,5-dihydro-6-methyl-4-propyl-s-triazolo-(1,5-A)-pyrimidin-5-one Caswell No. 033E
  • Triazolopyrimidinones
  • 2-AMINO-6-METHYL-4-PROPYL-[1,2,4]TRIAZOLO[1,5- AJPYRIMIDIN-5-ONE
  • 27277-00-5
  • C3H13F5O
  • C9H13N5O
  • Biochemicals and Reagents
  • BioChemical
  • Enzymes, Inhibitors, and Substrates
  • Enzyme Inhibitors by Enzyme
  • Enzyme Inhibitors
  • Phosphodiesterase IV
  • P to Q
  • Cyclic Nucleotide related
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