成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

6-pentadecylsalicylic acid

6-pentadecylsalicylic acid Struktur
16611-84-0
CAS-Nr.
16611-84-0
Englisch Name:
6-pentadecylsalicylic acid
Synonyma:
Anachardic acid;NSC 623096;NSC 333857;NSC 229596;22:0-Anacardic acid;Anacardic Acid 15:0;(15:0)-Anacardic acid;Cyclogallipharic acid;PENTADECYLSALICYLICACID;Hydrogenated anacardic acid
CBNumber:
CB01364624
Summenformel:
C22H36O3
Molgewicht:
348.52
MOL-Datei:
16611-84-0.mol

6-pentadecylsalicylic acid Eigenschaften

Schmelzpunkt:
90-91℃
Siedepunkt:
474.8±33.0 °C(Predicted)
Dichte
1.002
storage temp. 
-20°C
L?slichkeit
DMSO: ≥20mg/mL
Aggregatzustand
White solid
pka
3.08±0.30(Predicted)
Farbe
white to beige
Stabilit?t:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
InChIKey
ADFWQBGTDJIESE-UHFFFAOYSA-N
LogP
9.960 (est)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xi
R-S?tze: 36
S-S?tze: 26
WGK Germany  3
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
Sicherheit
P264 Nach Gebrauch gründlich waschen.
P264 Nach Gebrauch gründlich waschen.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P302+P352 BEI BERüHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckm??ig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.
P332+P313 Bei Hautreizung: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen.
P337+P313 Bei anhaltender Augenreizung: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen.

6-pentadecylsalicylic acid Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Anacardic acid, isolated from cashew shells or several other medicinal plants, is the general name given to a family of four different 6-alkyl salicyclic acids having varying degrees of unsaturation in the 15-carbon alkyl chain. These compounds are associated with anti-inflammatory, anti-tumor, molluscicidal, and anti-microbial activity. Literature frequently sites and gives the name anacardic acid to the completely-saturated compound (6-pentadecyl salicylic acid). Anacardic acid inhibits the histone acetyltransferase (HAT) activity of the transcription co-activators p300 and p300/CREB-binding protein-associated factor (PCAF) with IC50 values of 8.5 and 5 μM, respectively. At 25 μmol/L, anacardic acid suppresses NF-κB activation, inhibits IκB-α phosphorylation, and prohibits p65 nuclear translocation in KBM-5 cells.

Verwenden

Anacardic acid, isolated from cashew shells or several other medicinal plants, is the general name given to a family of four different 6-alkyl salicyclic acids having varying degrees of unsaturation in the 15-carbon alkyl chain. These compounds are associated with anti-inflammatory, anti-tumor, molluscicidal, and anti-microbial activity. Literature frequently sites and gives the name anacardic acid to the completely-saturated compound (6-pentadecyl salicylic acid). Anacardic acid inhibits the histone acetyltransferase (HAT) activity of the transcription co-activators p300 and p300/CREB-binding protein-associated factor (PCAF) with IC50 values of 8.5 and 5 μM, respectively. At 25 μmol/L, anacardic acid suppresses NF-κB activation, inhibits IκB-α phosphorylation, and prohibits p65 nuclear translocation in KBM-5 cells.[Cayman Chemical]

Allgemeine Beschreibung

A cell-permeable ginkgolic acid (Cat. No. 345887) analog that inhibits protein SUMO (Cat. Nos. 662037, 662039, and 662042) modification (IC50 = 2.2 μM using RanGAP1-C2 as substrate) in an ATP-dependent manner by selectively targeting SUMO-activating enzyme E1 (Cat. Nos. 662073 and 662074) and interfering with E1-SUMO intermediate formation. Both anacardic acid and ginkgolic acid are shown to effectively decrease overall SUMOylation of 293T cellular proteins in a dose-dependent manner, while neither compound is effective in affecting overall cellular protein ubiquitination or histone H4K8 acetylation in 293T cultures, although anacardic acid is shown to inhibit p300 (Cat. No. 506200) and PCAF (Cat. No. 124026) histone acetyltransferase activities in cell-free acetylase assays (by 82% and 86%, respectively, at 10 μM). Also reported to inhibit the activity of prostaglandin synthase, tyrosinase, and lipoxygenase, as well as to enhance Aurora kinase A (Cat. No. 481413), but not Aurora kinase B, autophosphorylation and kinase activity by inducing conformation change and enhancing ATP binding.

6-pentadecylsalicylic acid Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


6-pentadecylsalicylic acid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 155)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795
ivan@atkchemical.com China 32956 60
Chengdu GLP biotechnology Co Ltd
028-87075086 13350802083
scglp@glp-china.com CHINA 1824 58
Chengdu Biopurify Phytochemicals Ltd.
+8618080483897
sales@biopurify.com China 3772 58
Nanjing Dolon Biotechnology Co.,Ltd.
18905173768
sales@dolonchem.com CHINA 2972 58
Hubei Jusheng Technology Co.,Ltd.
18871490254
linda@hubeijusheng.com CHINA 28172 58
Shanghai Standard Technology Co., Ltd.
18502101150
ft-sales@nature-standard.com CHINA 1923 58
Wuhan ChemNorm Biotech Co.,Ltd.
+86-27-8439 4403 18971486879
sales@chemnorm.com CHINA 2935 58
Hubei Ipure Biology Co., Ltd
+8613367258412
ada@ipurechemical.com China 10319 58
HONG KONG IPURE BIOLOGY CO.,LIMITED
86 18062405514 18062405514
ada@ipurechemical.com CHINA 3461 58
Aktin Chemicals, Inc.
028-85159085
info@aktinchem.com CHINA 1025 58

16611-84-0()Verwandte Suche:


  • NSC 333857
  • NSC 623096
  • (15:0)-Anacardic acid
  • Ginkgolic Acid 15:0 〔Anacardic Acid 15:0〕
  • Hodrogenated anacardic acid
  • PENTADECYLSALICYLICACID
  • 6-Pentadecyl-2-hydroxybenzoic acid
  • Cyclogallipharic acid
  • Benzoic acid, 2-hydroxy-6-pentadecyl-
  • 22:0-Anacardic acid
  • Hydrogenated anacardic acid
  • NSC 229596
  • Anacardic acid A - Pentadecylsalicylic acid, 6-
  • Anacardic Acid - CAS 16611-84-0 - Calbiochem
  • 6-pentadecylsalicylic acid USP/EP/BP
  • Anacardic Acid 15:0
  • Anacardic Acid (Hydroginkgolic acid)
  • Ginkgolic acid (C15:0)/Anacardic acid
  • Anachardic acid
  • Bacterial,HATs,inhibit,HAT,Anacardic Acid,Histone Acetyltransferase,Ginkgolic Acid C15:0,Epigenetic Reader Domain,Inhibitor
  • N-Nitroso Bupivacaine EP Impurity B
  • 16611-84-0
  • Inhibitors
Copyright 2019 ? ChemicalBook. All rights reserved