PHENYL-D5-BORONIC ACID
|
|
PHENYL-D5-BORONIC ACID Eigenschaften
- Schmelzpunkt:
- 217-220 °C(lit.)
- L?slichkeit
- Chloroform (Slightly), DMSO
- Aggregatzustand
- solid
- Farbe
- White
- Stabilit?t:
- Hygroscopic
- InChI
- InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H
- InChIKey
- HXITXNWTGFUOAU-RALIUCGRSA-N
- SMILES
- B(C1C([H])=C([H])C([H])=C([H])C=1[H])(O)O
- CAS Datenbank
- 215527-70-1
Sicherheit
Kennzeichnung gef?hrlicher | Xn | ||
---|---|---|---|
R-S?tze: | 22 | ||
S-S?tze: | 36 | ||
WGK Germany | 3 | ||
HS Code | 2931900090 |
PHENYL-D5-BORONIC ACID Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R22:Gesundheitssch?dlich beim Verschlucken.S-S?tze Betriebsanweisung:
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.Verwenden
Phenylboronic Acid-d5 is the isotope labelled analog of Phenylboronic Acid; a compound used in the organic synthesis of various pharmaceutical goods.Synthese
A dry three-neck flask equipped with a rubber septum, an addition funnel equipped with a rubber septum, and a condenser was charged under nitrogen with magnesium turnings. To the addition funnel was added D5-bromobenzene (6.5 mL, 62 mmol) (Aldrich) dissolved in a 1:1 mixture of THF/toluene (31 mL). Grignard reagent formation was observed after about after about 1 mL of the contents of the addition funnel had been added to the magnesium turnings. The remaining bromobenzene solution was added dropwise over a period of about 1 h. After the addition was complete the reaction mixture was heated at 70° C. for 1 h. The reaction mixture was cooled to room temperature and added via a canulating needled to an addition funnel on a second three-neck flask containing a solution of triethylborate (B(OEt)3) (10.5 mL, 62 mmol) in toluene (10 mL) maintained at 0° C. The solution of the freshly prepared Grignard reagent was then added dropwise to the solution of triethylborate over a period of 1 h. The cooling bath was then removed and the reaction mixture was allowed to stir at room temperature for 15 h. The reaction mixture was quenched with 10% H2SO4 (30 mL) and stirred at room temperature for 1 h. The layers were separated and the organic layer was dried over Na2SO4. After removal of the solvent, addition of hexane precipitated the product as an off-white solid, which was collected by filtration and dried to afford Phenyl-d5-boronic acid. Its yield: 3.50 g, 45%.PHENYL-D5-BORONIC ACID Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Brom(2H5)benzol
BROMO(PHENYL-D5)MAGNESIUM
Triisopropylborat
Trimethylborat
Wasser
(2H6)Benzol
Triethylborat
Downstream Produkte
PHENYL-D5-BORONIC ACID Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 165)Lieferanten
Firmenname | Telefon | Land | Produktkatalog | Edge Rate | |
---|---|---|---|---|---|
Peric Technology Co.,Ltd | +86-0310-7183483 +8615030098277 |
jiake718@aliyun.com | China | 36 | 58 |
Yurui (Shanghai) Chemical Co., Ltd. | +86-021-50456736 +8613761615711 |
yuki@riyngroup.com | China | 1028 | 58 |
Kindchem(Nanjing)Co.,Ltd | +86-025-025-85281586 +8618651653755 |
sales@kindchem.cn | China | 1226 | 58 |
Shanghai UCHEM Inc. | +862156762820 +86-13564624040 |
sales@myuchem.com | China | 7388 | 58 |
Hebei Xinsheng New Material Technology Co., LTD. | +86-16632316109 |
xinshengkeji@xsmaterial.com | China | 1085 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 20288 | 58 |
Hebei Mojin Biotechnology Co.,Ltd | +86-15028179902 |
angelia@hbmojin.com | China | 1179 | 58 |
Springchem New Material Technology Co.,Limited | +86-021-62885108 +8613917661608 |
info@spring-chem.com | China | 2068 | 57 |
Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 |
sales@capot.com | China | 29791 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 18648 | 58 |
215527-70-1()Verwandte Suche:
[2H4]Tetrahydro[2H4]furan
(2H5)Pyridin
Brom(2H5)benzol
(2H5)Benzoesure
Iod(2H3)methan
(2H6)Benzol
Dichlor(2H2)methan
[2H4]Acetaldehyd
(2H8)Toluol
Borsure
- PHENYL-D5-BORONIC ACID
- phenyl-d5-boronicacid98atom%d
- (Perdeuterophenyl)boronic acid
- B-(Phenyl-2,3,4,5,6-d5)boronic acid
- Boronic acid,B-(phenyl-2,3,4,5,6-d5)-
- 9-bromo-10-(phenyl-d5)anthracene
- PHENYL-D5-BORONIC ACID(D, 98%)
- 2,3,4,5,6-Pentadeuteriumbenzeneboronic Acid
- Phenyl-d?-boronic acid
- Deuterated phenylboronic acid
- (2,3,4,5,6-pentadeuteriophenyl)boronic acid
- B-(phenyl-2,3,4,5,6-d5)-
- 215527-70-1
- C6D5H2BO2
- C6D5BOH2
- C6H2BD5O2
- Organometallic Reagents
- Aryl
- Boronic Acids and Derivatives
- Boronic Acids
- Boronic Acids
- blocks
- BoronicAcids
- Aryl
- Boronic Acids
- Boronic Acids and Derivatives