雙吲哚馬來酰亞胺 IV
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- CAS號:
- 119139-23-0
- 英文名:
- 3,4-Di-1H-indol-3-yl-1H-pyrrole-2,5-dione
- 英文別名:
- RO 31-6233;ARCYRIARUBIN A;3,4-Di(1H-indol-3-yl);BISINDOLYMALEIMIDE IV;BISINDOLYLMALEIMIDE IV;Sotrastaurin Impurity 13;3,4-BIS(3-INDOLYL)MALEIMIDE;2,3-BIS(1H-INDOL-3-YL)MALEIMIDE;BisindolylMaleiMide IV [Ro 31-6233];Bisindolylmaleimide IV, PKC inhibitor
- 中文名:
- 雙吲哚馬來酰亞胺 IV
- 中文別名:
- 二吲哚馬來酰亞胺IV;雙吲哚馬來酰亞胺 IV;雙辛基馬來酰亞胺 IV;2,3-雙(1H-吲哚-3-基)馬來酰亞胺;3,4-二(3-吲哚基)-1H-吡咯-2,5-二酮;雙吲哚馬來酰亞胺 IV,10 MM DMSO 溶液;BISINDOLYLMALEIMIDE IV,PKC抑制劑
- CBNumber:
- CB9354568
- 分子式:
- C20H13N3O2
- 分子量:
- 327.34
- MOL File:
- 119139-23-0.mol
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雙吲哚馬來酰亞胺 IV化學性質(zhì)
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熔點:
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161 °C
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沸點:
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690.1±55.0 °C(Predicted)
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密度:
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1.486±0.06 g/cm3(Predicted)
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儲存條件:
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-20°C
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溶解度:
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DMSO: soluble
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形態(tài):
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solid
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酸度系數(shù)(pKa):
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8.44±0.60(Predicted)
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顏色:
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dark red
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生物來源:
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synthetic (organic)
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雙吲哚馬來酰亞胺 IV性質(zhì)、用途與生產(chǎn)工藝
Bisindolylmaleimide IV (Arcyriarubin A) 是一種有效的蛋白激酶 C (PKC) 抑制劑，其 IC50 范圍為 0.1-0.55 μM。Bisindolylmaleimide IV 也抑制 PKA (IC50=3.1-11.8 μM)。Bisindolylmaleimide IV 在細胞培養(yǎng)中，是有效的人巨細胞病毒 (HCMV) 復制的抑制劑，IC50為 0.2 μM。
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PKC
0.1-0.55 μM (IC
50
)
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HCMV
0.2 μM (IC
50
)
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Bisindolylmaleimide IV (Arcyriarubin A) inhibits PKC with an IC
50
of 0.1 μM in 1 % DMSO, while the IC
50
of 0.55 μM in 10 % DMSO.
雙吲哚馬來酰亞胺 IV
上下游產(chǎn)品信息
上游原料
下游產(chǎn)品
| 更新日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS編號 | 包裝 | 價格 |
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| 2024/11/08 | HY-108254 | Bisindolylmaleimide IV | | 1 mg | 285元 |
| 2024/11/08 | HY-108254 | Bisindolylmaleimide IV | | 5 mg | 700元 |
119139-23-0, 雙吲哚馬來酰亞胺 IV 相關(guān)搜索:
- 抑制劑
- 生化試劑
- 有機原料-酰胺
- Serine/Threonine Kinase Inhibitors
- Protein Kinase C (PKC)
- Kinase/Phosphatase Biology
- Cell Biology
- BioChemical
- Cell Signaling and Neuroscience
- C20H13N3O2
- 雙吲哚馬來酰亞胺 IV,10 MM DMSO 溶液
- BISINDOLYLMALEIMIDE IV,PKC抑制劑
- 雙辛基馬來酰亞胺 IV
- 3,4-二(3-吲哚基)-1H-吡咯-2,5-二酮
- 2,3-雙(1H-吲哚-3-基)馬來酰亞胺
- 二吲哚馬來酰亞胺IV
- 雙吲哚馬來酰亞胺 IV
- 119139-23-0
- Bisindolylmaleimide IV, 10 mM in DMSO
- Bisindolylmaleimide IV, PKC inhibitor
- Sotrastaurin Impurity 13
- 3,4-Di(3-indolyl)-1H-pyrrole-2,5-dione
- Bisindolylmaleimide IV (Arcyriarubin A)
- Bisindolylmaleimide IV - CAS 119139-23-0 - Calbiochem
- 3,4-Di-1H-indol-3-yl-1H-pyrrole-2,5-dione
- BISINDOLYMALEIMIDE IV
- ARCYRIARUBIN A
- BISINDOLYLMALEIMIDE IV
- 3,4-Di(1H-indol-3-yl)
- 3,4-Bis(1H-indol-3-yl)pyrrole-2,5-dione
- bisindolylmaleimide iv:2,3-bis(1h-indol-3-yl)maleimide: 3,4-di-1h-indol-3-yl-1h-pyrrole-2,5-dione
- BisindolylMaleiMide IV [Ro 31-6233]
- 1H-Pyrrole-2,5-dione, 3,4-di-1H-indol-3-yl-
- 3,4-Bis(1H-indol-3-yl)-1H-pyrrole-2,5-dione
- 3-(1H-Indole-3-yl)-4-(1H-indole-3-yl)-1H-pyrrole-2,5-dione
- 3,4-BIS(3-INDOLYL)MALEIMIDE (ARCYRIARUBIN A).
- 3,4-BIS(3-INDOLYL)MALEIMIDE (ARCYRIARUBIN A), 95+%
- 2,3-BIS(1H-INDOL-3-YL)MALEIMIDE
- 3,4-BIS(3-INDOLYL)MALEIMIDE
- RO 31-6233