4-[(3-氯-4-氟苯基)氨基]-6-[(3-吡啶甲基)氨基]-1,7-萘啶-3-甲腈
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- CAS號:
- 871307-18-5
- 英文名:
- 4-[(3-Chloro-4-fluorophenyl)amino]-6-[(3-pyridinylmethyl)amino]-1,7-naphthyridine-3-carbonitrile
- 英文別名:
- TC-S 7006;Tpl2-IN-2p;Tpl2 Kinase Inhibitor;Tpl2 Kinase Inhibitor 1;Tpl2 Kinase Inhibitor 1,Tpl-2 Kinase Inhibitor 1;4-(3-chloro-4-fluorophenylamino)-6-(pyridin-3-ylmethylamino)-1,7-naphthyridine-3-carbonitrile;4-[(3-Chloro-4-fluorophenyl)amino]-6-[(3-pyridinylmethyl)amino]-1,7-naphthyridine-3-carbonitrile;1,7-Naphthyridine-3-carbonitrile, 4-[(3-chloro-4-fluorophenyl)amino]-6-[(3-pyridinylmethyl)amino]-
- 中文名:
- 4-[(3-氯-4-氟苯基)氨基]-6-[(3-吡啶甲基)氨基]-1,7-萘啶-3-甲腈
- 中文別名:
- 化合物 T17145;化合物 TPL2 KINASE INHIBITOR 1;4-(3-氯-4-氟苯胺)-6-(吡啶-3-甲胺) -3-氰基-1,7-萘雜環(huán);4-[(3-氯-4-氟苯基)氨基]-6-[(3-吡啶甲基)氨基]-1,7-萘啶-3-甲腈;4-((3-氯-4-氟苯基)氨基)-6-((吡啶-3-基甲基)氨基)-1,7-萘啶-3-甲腈
- CBNumber:
- CB41458318
- 分子式:
- C21H14ClFN6
- 分子量:
- 404.83
- MOL File:
- 871307-18-5.mol
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4-[(3-氯-4-氟苯基)氨基]-6-[(3-吡啶甲基)氨基]-1,7-萘啶-3-甲腈化學性質(zhì)
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沸點:
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616.3±55.0 °C(Predicted)
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密度:
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1.45
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儲存條件:
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2-8°C
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溶解度:
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DMF: 1 mg/ml; DMF:PBS(pH7.2) (1:2): 0.33 mg/ml; DMSO: 1 mg/ml
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形態(tài):
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A crystalline solid
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酸度系數(shù)(pKa):
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4.80±0.10(Predicted)
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顏色:
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Yellow to green
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4-[(3-氯-4-氟苯基)氨基]-6-[(3-吡啶甲基)氨基]-1,7-萘啶-3-甲腈性質(zhì)、用途與生產(chǎn)工藝
Tpl2 Kinase Inhibitor 1 (Compound 1) 是一種有效的選擇性 Tpl2 (COT 激酶，MAP3K8) 抑制劑，可用于炎癥反應和某些癌癥的研究。
Cancer Osaka thyroid (COT) kinase (Tpl2) is an important regulator of pro-inflammatory cytokines in macrophages.
4-[(3-氯-4-氟苯基)氨基]-6-[(3-吡啶甲基)氨基]-1,7-萘啶-3-甲腈
上下游產(chǎn)品信息
上游原料
下游產(chǎn)品
| 更新日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS編號 | 包裝 | 價格 |
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| 2024/11/08 | HY-12358 | Tpl2 Kinase Inhibitor 1 | | 1 mg | 1872元 |
| 2024/11/08 | HY-12358 | 4-[(3-氯-4-氟苯基)氨基]-6-[(3-吡啶甲基)氨基]-1,7-萘啶-3-甲腈
Tpl2 Kinase Inhibitor 1 | 871307-18-5 | 5mg | 5150元 |
4-[(3-氯-4-氟苯基)氨基]-6-[(3-吡啶甲基)氨基]-1,7-萘啶-3-甲腈
生產(chǎn)廠家
871307-18-5, 4-[(3-氯-4-氟苯基)氨基]-6-[(3-吡啶甲基)氨基]-1,7-萘啶-3-甲腈 相關搜索:
- 抑制劑
- C21H14ClFN6
- 化合物 TPL2 KINASE INHIBITOR 1
- 4-((3-氯-4-氟苯基)氨基)-6-((吡啶-3-基甲基)氨基)-1,7-萘啶-3-甲腈
- 化合物 T17145
- 4-[(3-氯-4-氟苯基)氨基]-6-[(3-吡啶甲基)氨基]-1,7-萘啶-3-甲腈
- 4-(3-氯-4-氟苯胺)-6-(吡啶-3-甲胺) -3-氰基-1,7-萘雜環(huán)
- 871307-18-5
- Tpl2 Kinase Inhibitor 1,Tpl-2 Kinase Inhibitor 1
- Tpl2 Kinase Inhibitor 1
- 1,7-Naphthyridine-3-carbonitrile, 4-[(3-chloro-4-fluorophenyl)amino]-6-[(3-pyridinylmethyl)amino]-
- TC-S 7006
- Tpl2-IN-2p
- 4-[(3-Chloro-4-fluorophenyl)amino]-6-[(3-pyridinylmethyl)amino]-1,7-naphthyridine-3-carbonitrile
- Tpl2 Kinase Inhibitor
- 4-(3-chloro-4-fluorophenylamino)-6-(pyridin-3-ylmethylamino)-1,7-naphthyridine-3-carbonitrile