96020-91-6
基本信息
鹽酸依氟鳥氨酸一合水
依氟鳥氨酸鹽酸鹽一水物
鹽酸依氟鳥氨酸一水合物
依氟鳥氨酸鹽酸鹽一水合物
依氟鳥氨酸鹽酸鹽一水合酸物
依氟鳥氨酸鹽酸鹽一水合物99%
2-二氟甲基-DL-鳥氨酸鹽酸鹽一水合物
2,5-二氨基-2-(二氟甲基)五烯酸鹽酸鹽水合物
Unii-4nh22ndw9h
DFMO EFLORNITHINE
Eflornithine HCl API
Eflornithine HCl hydrate
DMFO HCl/Eflornithine HCl
Eflornithine HCl Monohydrate
MDL-71782 hydrochloride hydrate
RMI-71782 hydrochloride hydrate
Eflornithine hydrochloride salt
物理化學性質(zhì)
報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
2024/11/08 | 46270 | 依氟鳥氨酸鹽酸鹽一水合物 Eflornithine hydrochloride monohydrate | 96020-91-6 | 1g | 431元 |
2024/11/08 | 46270 | 依氟鳥氨酸鹽酸鹽一水合物 Eflornithine hydrochloride monohydrate | 96020-91-6 | 5g | 1221元 |
2024/11/08 | 46270 | 依氟鳥氨酸鹽酸鹽一水合物 Eflornithine hydrochloride monohydrate | 96020-91-6 | 25g | 5173元 |
常見問題列表
Target | Value |
Orn decarboxylase |
用α-difluoromethyl-Orn處理BY2細胞,抑制其過氧化氫的產(chǎn)生,但并沒有發(fā)生程序性細胞死亡。
Eflornithine is the only new molecule registered for the treatment of human African trypanosomiasis over the last 50 years. It is the drug used mainly as a back-up for melarsoprol refractory Trypanosoma brucei gambiense cases. In subjects with excessive, unwanted facial hair, eflornithine 15% cream is superior to placebo in reducing hair growth. After 24 weeks' treatment, 58% of eflornithine and 34% of placebo subjects have at least some improvement in facial hirsutism. The hair growth inhibitory activity of eflornithine is significantly enhanced when the eflornithine cream is applied onto a mouse skin area pretreated with microneedles. Treatment of coarctation hypertensive rats with eflornithine results in a normalization of the contractile intensity to KCI and norepinephrine and relaxations to acetylcholine by 14 days of hypertension.