866084-31-3
中文名稱
2-甲基-2-丙基-4-(6 - {[8-環(huán)戊基-5-甲基-7-氧代-6-(1-丁氧乙烯基)-7,8-二氫吡啶并[2,3-D]嘧啶-2-基]氨基} -3-吡啶基)-1-哌嗪甲酸
英文名稱
tert-butyl 4-(6-(8-cyclopentyl-5-Methyl-7-oxo-6-(1-propoxyvinyl)-7,8-dihydropyrido[2,3-d]pyriMidin-2-ylaMino)pyridin-3-yl)piperazine-1-carboxylate
CAS
866084-31-3
分子式
C33H45N7O4
分子量
603.75
MOL 文件
866084-31-3.mol
更新日期
2024/10/31 10:02:07
866084-31-3 結(jié)構(gòu)式
基本信息
中文別名
帕博西尼雜質(zhì)73帕布西利布中間體2
帕布昔利布中間體二
帕布昔利布中間體2
帕布西利布-中間體7
帕布昔利布標(biāo)準(zhǔn)品017
2-甲基-2-丙基-4-(6-{[8-環(huán)戊基-5-甲基-7-氧代-6-(1-丁氧乙烯基)-7,8-二
4-{6-[(6-(1-丁氧基乙烯基)-8-環(huán)戊基-5-甲基-7-氧代-7,8-二氫吡啶[2,3-D]嘧啶-2-基胺基)吡啶-3-基)哌嗪-1-甲酸叔丁酯
4-(6-(8-環(huán)戊基-6-(1-正丁氧基乙烯基)-7,8-二氫-5-甲基-7-氧代吡啶并[2,3-D]嘧啶-2-基氨基)吡啶-3-基)哌嗪-1-羧酸叔丁酯
4-(6-((6-(1-丁氧基乙烯基C-8-環(huán)戊基-5-甲基-7-氧代-7,8-二氫吡啶并[2,3-D]嘧啶-2-基C氨基)吡啶-3-基)哌嗪-1-甲酸叔丁酯
英文別名
Palbociclib-017Palbociclib INT
Palbociclib Impurity 73
tert-butyl 4-(6-(8-cyclopentyl-5-Methyl-7-oxo-6-(1-propoxyvinyl)-7,8-dihydropyrido[2,3-d]pyriMidin-2
tert-butyl 4-(6-(8-cyclopentyl-5-Methyl-7-oxo-6-(1-propoxyvinyl)-7,8-dihydropyrido[2,3-d]pyriMidin-2-ylaMino)pyridin-3-yl)piperazine-1-carboxylate
tert-butyl 4-(6-((6-(1-butoxyvinyl)-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carboxylate
4-[6-[[6-(1-Butoxyvinyl)-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl]amino]pyridin-3-yl]piperazine-1-carboxylic acid tert-butyl ester
2-Methyl-2-propanyl 4-(6-{[8-cyclopentyl-5-methyl-7-oxo-6-(1-prop oxyvinyl)-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl]amino}-3-pyridin yl)-1-piperazinecarboxylate
1-Piperazinecarboxylic acid, 4-[6-[[6-(1-butoxyethenyl)-8-cyclopentyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl]amino]-3-pyridinyl]-, 1,1-dimethylethyl ester
Palbociclib impurity 19/Tert-butyl 4-(6-((6-(1-butoxyvinyl)-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carboxylate
所屬類別
醫(yī)藥中間體：原料藥中間體物理化學(xué)性質(zhì)
沸點(diǎn)764.2±70.0 °C(Predicted)
密度1.224±0.06 g/cm3(Predicted)
儲(chǔ)存條件Keep in dark place,Sealed in dry,2-8°C
溶解度DMSO（微溶、加熱、超聲處理）、甲醇（微溶、超聲處理）
酸度系數(shù)(pKa)5.24±0.10(Predicted)
形態(tài)固體
顏色淡黃色
穩(wěn)定性感光
InChIKeySCWKOLRZBMGTNT-UHFFFAOYSA-N
SMILESN1(C(OC(C)(C)C)=O)CCN(C2=CC=C(NC3=NC=C4C(C)=C(C(OCCCC)=C)C(=O)N(C5CCCC5)C4=N3)N=C2)CC1