83930-33-0
基本信息
Urotensin IUrotens
Catostomus urotensin I
urotensin i teleost fish
Urotensin I, ≥95% (HPLC)
Urotensin I (Catostomuscommersoni) (9CI)
NDDPPISIDLTFHLLRNMIEMARIENEREQAGLNRKYLDEV-NH2
ASN-ASP-ASP-PRO-PRO-ILE-SER-ILE-ASP-LEU-THR-PHE-HIS-LEU-LEU-ARG-ASN-MET-ILE-GLU-MET-ALA-ARG-ILE-GLU-ASN-GLU-ARG-GLU-GLN-ALA-GLY-LEU-ASN-ARG-LYS-TYR-LEU-ASP-GLU-VAL-NH2
H-ASN-ASP-ASP-PRO-PRO-ILE-SER-ILE-ASP-LEU-THR-PHE-HIS-LEU-LEU-ARG-ASN-MET-ILE-GLU-MET-ALA-ARG-ILE-GLU-ASN-GLU-ARG-GLU-GLN-ALA-GLY-LEU-ASN-ARG-LYS-TYR-LEU-ASP-GLU-VAL-NH2
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2023/03/20 | HY-P1542 | 硬骨魚緊張肽 Urotensin I | 83930-33-0 | 500μg | 2600元 |
| 2023/03/20 | HY-P1542 | 硬骨魚緊張肽 Urotensin I | 83930-33-0 | 1mg | 4500元 |
| 2023/03/20 | HY-P1542 | 硬骨魚緊張肽 Urotensin I | 83930-33-0 | 5mg | 13500元 |
常見問題列表
pEC50: 11.46 (human CRF
1
, CHO cells), 9.36 (human CRF
2
, CHO cells), 9.85 (rat CRF
2α
, CHO cells)
Ki: 0.4 nM (hCRF
1
, cell assay), 1.8 nM (rCRF
2α
, cell assay), and 5.7 nM (mCRF
2β
, cell assay)
Urotensin I is 2-3 times more potent than CRF or sauvagine in stimulating ACTH release from a superfused goldfish anterior pituitary cell column.
Rat tail artery strips were incubated in the presence of 4 x 10(-3) M theophylline and Urotensin I (UI). At the concentrations of 1.50, 7.50 mU/ml but not of 0.75 mU/ml Urotensin I, the content of cAMP increased significantly.
Intraperitoneal injections of urotensin I, a CRF-like neuropeptide isolated from the caudal neurosecretory system of the teleost Catostomus commersoni, ovine CRF and sauvagine all produced significant increases in circulating levels of plasma cortisol in goldfish in which endogenous ACTH secretion was suppressed with betamethasone.