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802918-35-0

中文名稱 西那卡塞雜質(zhì)18
英文名稱 (R)-N-(1-(7,8-dihydronaphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine
CAS 802918-35-0
分子式 C22H24F3N
分子量 359.428
MOL 文件 802918-35-0.mol
802918-35-0 結(jié)構(gòu)式 802918-35-0 結(jié)構(gòu)式

基本信息

中文別名
西那卡塞雜質(zhì)18
西那卡塞雜質(zhì)15(單體)
西那卡塞雜質(zhì) CINACALCET
英文別名
"(R)-N-(1-(7,8-dihydronaphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)
(R)-1-(phthalen-1-yl)-N-(3-(trifluoromethyl)benzyl)ethan-1-aminehydrochloride
(R)-1-(naphthalen-1-yl)-N-(3-(trifluoromethyl)benzyl)ethan-1-aminehydrochloride
(R)-N-(1-(7,8-dihydronaphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine
1-(7,8-Dihydro-napthalen-1-yl)-ethyl]- [3-(3-trifluoromethyl-phenyl)]-amine hydrochloride
(αR)-7,8-Dihydro-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine
(E)-N-(1-(5,6-dihydronaphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)acrylamide hydrochloride
所屬類別
分析化學(xué):藥典標(biāo)準(zhǔn)品和雜質(zhì)標(biāo)準(zhǔn)品

應(yīng)用領(lǐng)域

用途一
(αR)-7,8-Dihydro-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine is synthetically prepared though a double bond migration in Heck reaction during the preparation of cinacalcet congeners. This enantiomerically pure material is seperated from its counter part, (αR)-5,6-Dihydro-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine (D455335) using HPLC.
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