572-31-6
中文名稱
黃杞苷
英文名稱
(2R,3R)-5,7-dihydroxy-2-(4-hydroxyphenyl)-3-[(2S,3R,4R,5S,6S)-3,4,5-trihydroxy-6-methyl-oxan-2-yl]oxy-chroman-4-one
CAS
572-31-6
分子式
C21H22O10
分子量
434.39
MOL 文件
572-31-6.mol
更新日期
2024/11/04 17:18:58
572-31-6 結(jié)構(gòu)式
基本信息
中文別名
黃杞苷對(duì)照品,黃杞苷(標(biāo)準(zhǔn)品)
黃杞苷, 來源于黃杞
ENGELETIN 黃杞苷
英文別名
EngelitinAroMadendrin 3-rhaMnoside
Dihydrokaempferol 3-rhamnoside
Dihydrokaempferol 3-O-alpha-L-rhamnopyranoside
Engeletin, 98%, from Engelhardtia Roxb.iana Lindl.
(+)-(2R,3R)-Dihydrokaempferol 3-O-alpha-L-rhamnoside
(2R,3R)-5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-3-yl 6-deoxy-alpha-L-mannopyranoside
4H-1-Benzopyran-4-one,3-[(6-deoxy-a-L-mannopyranosyl)oxy]-2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-,(2R,3R)-
4H-1-Benzopyran-4-one, 3-[(6-deoxy-α-L-mannopyranosyl)oxy]-2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-, (2R,3R)-
(2R,3R)-5,7-dihydroxy-2-(4-hydroxyphenyl)-3-[(2S,3R,4R,5S,6S)-3,4,5-trihydroxy-6-methyl-oxan-2-yl]oxy-chroman-4-one
物理化學(xué)性質(zhì)
外觀性狀類白色結(jié)晶性粉末，可溶于甲醇、乙醇、DMSO等有機(jī)溶劑，來源于土茯苓 Smilax glabra.菝葜。
熔點(diǎn)176-177℃
沸點(diǎn)763.4±60.0 °C(Predicted)
密度1.66
酸度系數(shù)(pKa)7.37±0.60(Predicted)
應(yīng)用領(lǐng)域
用途1
用于含量測(cè)定/鑒定/藥理實(shí)驗(yàn)等。藥理藥效:具有較強(qiáng)的利尿和鎮(zhèn)痛作用。
用途2
黃杞苷具有活血化瘀，降血脂，降血壓的作用。黃杞苷價(jià)格(試劑級(jí))
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2024/08/19 | S9170 | 黃杞苷 Engeletin | 572-31-6 | 1mg | 1204.8元 |
常見問題列表
生物活性
Engeletin 是從 hymenaea martiana 中得到的黃酮苷類物質(zhì)，能夠抑制 NF-κB 信號(hào)通路的激活，具有抗炎、鎮(zhèn)痛、利尿、消腫、抗菌等作用。靶點(diǎn)
| Target | Value |
|
NF-κB
() |
體外研究
Engeletin is a flavanonol glycoside isolated from hymenaea martiana , inhibits NF-κB signaling-pathway activation.
體內(nèi)研究
Engeletin (25, 50, 100 mg/kg, i.p.) markedly reduces LPS-increased myeloperoxidase activity in mice, activates NF-κB-pathway activation, decreases the production of inflammatory mediators (iNOS and COX-2), and suppresses the expression of TLR4-signaling downstream molecules such as MyD88, IRAK1, TRAF6, and TAK1 proteins.