482-45-1
基本信息
白芷甲素
異歐芹屬素乙
4-(3-甲基丁-2-烯氧基)呋喃并[3,2-g]苯并吡喃-7-酮
ISOIMPERATORIN
4-(3-Methyl-but-2-enyloxy-furo[3,2-g]chromen-7-one
ISOIMPERATORIN(P)
Isomperatorin
4-(3-Methylbut-2-enoxy)furo[3,2-g]chromen-7-one
4-(3-Methyl-but-2-enyloxy-furo[3,2-γ],chromen-7-one
7H-Furo[3,2-g][1]benzopyran-7-one, 4-[(3-methyl-2-
buten-1-yl)oxy]-
4-(Isopentenyloxy)-7H-furo[3,2-g][1]benzopyran-7-one
4-[(3-Methyl-2-butenyl)oxy]-7H-furo[3,2-g][1]benzopyran-7-one
Isoimperatoin
物理化學(xué)性質(zhì)
安全數(shù)據(jù)
常見(jiàn)問(wèn)題列表
異歐前胡素具有降壓、解痙、抗癌的作用,還可以治療銀屑病。
色譜柱:μbondapak C18柱(150mm×6mm, 5μm);流動(dòng)相:甲醇-乙腈-0.25mol/L磷酸溶液(9:5:10);流速:1.0ml/min;檢測(cè)波長(zhǎng):322nm;柱溫:室溫。
[供試品的制備]
取本品粗粉約50g,用8倍量90%乙醇回流提取3次,每次1.5h,合并提取液,回收乙醇,得浸膏13.70g,并將其與適量經(jīng)處理過(guò)的大孔吸附樹(shù)脂拌勻,置于經(jīng)處理過(guò)的大孔吸附樹(shù)脂柱上,依次用水,20%、30%、40%、50%、60%、70%、80%、90%的乙醇沖洗,每次沖至洗脫液無(wú)色,水浴蒸干,得膏狀物,分別用50%乙醇溶解,定容至50ml。按本法色譜條件進(jìn)行測(cè)定。
Target | Value |
AChE
(Cell-free assay) | 74.6 μM |
During a screening program for new agrochemicals from Chinese medicinal herbs, the ethanol extract of Notopterygium incisum rhizomes is found to possess strong nematicidal activity against the two species of nematodes, Bursaphelenchus xylophilus and Meloidogyne incognita . Based on bioactivity-guided fractionation, the four constituents are isolated from the ethanol extract and identified as Columbianetin, Falcarindiol, Falcarinol, and Isoimperatorin. Isoimperatorin also has LC 50 values of 21.83 μg/mL against B. xylophilus . When using 15 min UV light treatment, falcarindiol, falcarinol, and isoimperatorin demonstrated almost five times more toxic to the southern root-knot nematodes than in dark treatment while columbianetin showed only two times more toxic. isoimperatorin has been demonstrated to possess insecticidal activity against several insects, such as the cabbage aphid ( Brevicoryne brassicae ). Isoimperatorin is identified in the active fraction of Angelica dahurica (AD) extract. Isoimperatorin is usually used as the internal standard (IS).