444723-13-1
444723-13-1 結(jié)構(gòu)式
基本信息
4-((6-(環(huán)己基甲氧基)-7H-嘌呤-2-基)氨基)-N,N-二乙基苯甲酰胺
4-[[6-(cyclohexylmethoxy)-7H-purin-2-yl]amino]-N,N-diethylbenzamide
4-[[6-(Cyclohexylmethoxy)-1H-purin-2-yl]amino]-N,N-diethylbenzamide
Benzamide, 4-[[6-(cyclohexylmethoxy)-9H-purin-2-yl]amino]-N,N-diethyl-
物理化學性質(zhì)
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2024/08/19 | HY-107419 | NU6140 NU6140 | 444723-13-1 | 5mg | 1200元 |
| 2024/08/19 | HY-107419 | NU6140 NU6140 | 444723-13-1 | 10mM * 1mLin DMSO | 1320元 |
| 2024/08/19 | HY-107419 | NU6140 NU6140 | 444723-13-1 | 10 mg | 2000元 |
常見問題列表
|
cdk2-cyclin A 0.41 μM (IC 50 ) |
CDK1-Cyclin B 6.6 μM (IC 50 ) |
CDK4-Cyclin D 5.5 μM (IC 50 ) |
cdk5-p25 15 μM (IC 50 ) |
cdk7-cyclin H 3.9 μM (IC 50 ) |
Aurora A 67 nM (IC 50 ) |
Aurora B 35 nM (IC 50 ) |
NU6140 is less active on CDK1-cyclin B, CDK4-cyclin D, CDK5-p25 and CDK7-cyclin H, with IC
50
s of 6.6, 5.5, 15 and 3.9 μM, respectively.
NU6140 increases catalytic activity of capase-9 and capase-3, causes increase in the sub-G1 apoptotic cell population.