3200-06-4
3200-06-4 結(jié)構(gòu)式
基本信息
草酸萘呋胺
萘呋胺草酸鹽
草酸萘呋胺氫
萘呋胺酯草酸鹽
硝基呋喃草酸氫鹽
萘呋胺酯草酸鹽 標(biāo)準(zhǔn)品
Α-(1-萘基甲基)-2-四氫呋喃丙酸二乙氨基乙酯
Α-(1-萘甲基)-2-四氫呋喃丙酸二乙胺基乙基酯草酸鹽
alpha-(1-萘甲基)-2-四氫呋喃丙酸二乙胺基乙基酯草酸鹽
Iridus
eu-1806
CLARANTIN
Acid oxalate
NAFRONYL OXALATE
naftidrofuryloxalate
Nafronyl acid oxalate
hylester,oxalate(1:1)
NAFRONYL OXALATE SALT
物理化學(xué)性質(zhì)
常見(jiàn)問(wèn)題列表
萘呋胺酯草酸鹽為有機(jī)酸物質(zhì)，其是腦血管和外周血管的擴(kuò)張劑；拮抗5-羥色胺及緩激肽的作用；可使細(xì)胞內(nèi)ATP增多以改善細(xì)胞代謝；降低血液及血漿的粘稠度及纖維蛋白原濃度；增加細(xì)胞的氧化能力，對(duì)細(xì)胞缺氧具保護(hù)作用；此外具有罌粟堿樣的解痙作用，緩慢而持久。
萘呋胺酯草酸鹽是一種用于治療心腦血管與周?chē)芗膊〉乃幬?，具有如下特點(diǎn)：其擴(kuò)張作用比煙酸強(qiáng)，增強(qiáng)腦血管流量的作用較罌粟緩慢而持久。據(jù)認(rèn)為其臨床應(yīng)用比罌粟堿安全，對(duì)嚴(yán)重下肢動(dòng)脈炎的療效較煙胺羥丙茶堿顯著而迅速。
萘呋胺酯草酸鹽是一種用于治療心腦血管與周?chē)芗膊〉乃幬?。其具有如下特點(diǎn)：其擴(kuò)張作用比煙酸強(qiáng)，增強(qiáng)腦血管流量的作用較罌粟緩慢而持久。
| Target | Value |
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5-HT2 receptor
() |
Naftidrofuryl oxalate (Nafronyl oxalate salt) may be effective for relieving the pain of muscle cramps.
Naftidrofuryl oxalate (Nafronyl oxalate salt) is the only vasoactive drug for peripheral arterial disease (PAD) which is likely to be cost-effective.
Naftidrofuryl oxalate (Nafronyl oxalate salt) is ranked first for both maximum walking distance (MWD) and pain-free walking distance (PFWD) (probability of 0·947 and 0·987, respectively, of being the best treatment) followed by cilostazol and pentoxifylline. Naftidrofuryl oxalate (Nafronyl oxalate salt) is effective treatments for claudication, Naftidrofuryl oxalate is likely to be the most effective, with minimal serious adverse events.