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31362-50-2

中文名稱 蛙皮素
英文名稱 Bombesin
CAS 31362-50-2
分子式 C71H110N24O18S
分子量 1619.85
MOL 文件 31362-50-2.mol
更新日期 2024/12/22 20:23:43
31362-50-2 結(jié)構(gòu)式 31362-50-2 結(jié)構(gòu)式

基本信息

中文別名
黃蛙素
蛙皮素
鈴蟾肽
兩棲藍(lán)素
蛙皮素,胃泌素
英文別名
BOMBESIN
bombesin acetate
BOMBESIN ACOH 7H2O
Bombesin, Free Base
PYR-QRLGNQWAVGHLM-NH2
BOMBESIN ACETATE SALT
bombesin acetate hydrate
Bombesin acetate salt hydrate
M.W. 1619.85 C71H110N24O18S
Bombesin hydrate acetate salt
所屬類別
生物化工:多肽

物理化學(xué)性質(zhì)

密度1.50±0.1 g/cm3(Predicted)
儲存條件−20°C
溶解度0.05 M acetic acid: 20 mg/mL, clear, colorless
酸度系數(shù)(pKa)13.04±0.46(Predicted)
形態(tài)粉末
顏色White to off-white
Merck13,1320
BRN9611365
序列Pyr-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2

安全數(shù)據(jù)

安全說明22-24/25
WGK Germany3
RTECS號BD3480000
蛙皮素價(jià)格(試劑級)
報(bào)價(jià)日期產(chǎn)品編號產(chǎn)品名稱CAS號包裝價(jià)格
2024/11/11XW313625022蛙皮素31362-50-225MG1148元
2024/11/11XW313625021蛙皮素31362-50-25MG369元
2024/11/08HY-P0195蛙皮素
Bombesin
31362-50-21mg900元

常見問題列表

生物活性
Bombesin是一種最初從青蛙皮膚中分離的十四肽; 在胃泌素釋放和G蛋白受體活化中起重要作用。
體外研究

Bombesin is a tetradecapeptide with a COOH terminus ending in Gly-His-Leu-Met-NH2 and subsequently is shown to closely resemble two mammalian bombesin -related peptides, gastrin-releasing peptide (GRP) and neuromedin B (NMB). Bombesin is found to have stimulatory effects upon gastric and pancreatic secretions, release of gastrointestinal hormones, gallbladder contraction and bronchoconstriction. It is present in amphibian gastric endocrine cells, avian proventriculus endocrine cells and avian brain. In mammals it is present mainly in nerve cells and fibers. The only mammalian endocrine cell shown to date to have bombesin is the P-cell in fetal lung. Bombesin is also found in mammalian brain, with its highest concentration in the hypothalamus. Bombesin is shown to be a potent mitogen for Swiss 3T3 cells. In the presence of a low concentration (3.5%) of serum, bombesin stimulates 3T3 cell proliferation. In serum-free medium, bombesin induces DNA synthesis in the absence of any other added growth factor (IC 50 =1 nM).

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