298-93-1
中文名稱(chēng)
噻唑蘭
英文名稱(chēng)
Thiazolyl Blue
CAS
298-93-1
EINECS 編號(hào)
206-069-5
分子式
C18H18BrN5S
MDL 編號(hào)
MFCD00011964
分子量
416.34
MOL 文件
298-93-1.mol
更新日期
2024/12/23 11:22:48
298-93-1 結(jié)構(gòu)式
基本信息
中文別名
2-(4,5-二甲基-2-噻唑基)-3,5-二苯基-2H-四唑氫溴酸鹽溴化噻唑基藍(lán)四唑
3-(4,5-二甲基-2-噻唑)-2,5-二苯基溴化四氮唑噻唑藍(lán)
噻唑藍(lán)(MTT)
噻唑蘭 MTT
MTT噻唑藍(lán)
3-(4,5-二甲基)25-二苯溴
噻唑藍(lán)溴化四唑
3-(4,5-二甲基-2-噻唑基)-2,5-二苯基-2H-四氮唑鎓溴化物
噻唑蘭
溴化噻唑藍(lán)四氮唑
3-(4,5-二甲基-2-噻唑基)-2,5-二苯基-2H-四氮唑溴化物
英文別名
3-(4,5-DIMETHYL-2-THIAZOL-2-YL)-2,5-DIPHENYL-2H-TETRAZOLIUM BROMIDE3-(4,5-DIMETHYL-2-THIAZOLYL)-2,5-DIPHENYL-2H-TETRAZOLIUM BROMIDE
3-(4,5-DIMETHYL-2-THIAZOLYL)-2,5-DIPHENYLTETRAZOLIUM BROMIDE
3-(4,5-DIMETHYLITHIAZOLYL-2)-2,5-DIPHENYL MONOTETRAZOLIUM BROMIDE
3-(4,5-DIMETHYLTHIAZOL-2-YL)-2,5-DIPHENYL-2H-TETRAZOLIUM BROMIDE
3,[4,5-DIMETHYLTHIAZOL-2-YL]-2,5-DIPHENYLTETRAZOLIUM BROMIDE
3-(4,5-DIMETHYLTHIAZOL-2-YL)-2,5-DIPHYL-2 H-TETRAZOLIUM BROMIDE
3-(4,5-DIMETHYLTHIAZOLYL-2)-2,5-DIPHENYL TETRAZOLIUM BROMIDE
METHYLTHIAZOLETETRAZOLIUM
METHYLTHIAZOLYLDIPHENYL-TETRAZOLIUM BROMIDE
MTT
THIAZOLE BLUE
THIAZOLYL BLUE
THIAZOLYL BLUE TETRAZOLIUM BROMIDE
THIAZOYL BLUE TETRAZOLIUM BROMIDE
2-(4,5-dimethyl-2-thiazolyl)-3,5-diphenyl-2h-tetrazoliubromide
2H-Tetrazolium,2-(4,5-dimethyl-2-thiazolyl)-3,5-diphenyl-,bromide
3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2h-tetrazoliubromide
mmttetrazolium
thiazolylbluemonotetrazolium
所屬類(lèi)別
化學(xué)試劑：偶氮、重氮化合物物理化學(xué)性質(zhì)
熔點(diǎn)195 °C (dec.) (lit.)
熔點(diǎn)195 °C (dec.)(lit.)
密度1.4886 (estimate)
儲(chǔ)存條件2-8°C
儲(chǔ)存條件2-8°C
溶解度methanol: 5 mg/mL, clear
溶解度在甲醇中可溶5 mg/mL，澄清
形態(tài)powder
顏色黃色到橙色
水溶解性Slightly soluble.Clear yellow solution at 5mg in 1ml of water on vortexing
水溶解性微溶
敏感性感光
最大波長(zhǎng)(λmax)378 nm, 242 nm
BRN3825277
穩(wěn)定性吸濕性
生物領(lǐng)域應(yīng)用Cell viability assay; microbial growth assays; DNA quantification assays; tissue viability assays; detecting enzymes; measuring membrane potential; treating Alzheimer’s disease,asthma,cancer
InChIKeyAZKSAVLVSZKNRD-UHFFFAOYSA-M
CAS 數(shù)據(jù)庫(kù)298-93-1(CAS DataBase Reference)
安全數(shù)據(jù)
警示詞警告
危險(xiǎn)性描述H315-H319-H335-H341
危險(xiǎn)品標(biāo)志Xi,T,Xn
危險(xiǎn)類(lèi)別碼46-68-36/37/38
安全說(shuō)明22-24/25-53-45-36/37-26
安全說(shuō)明S22-S24/25-S53-S45-S36/37-S26
WGK Germany3
RTECS號(hào)XF8060000
TSCAYes
海關(guān)編碼29341000
毒害物質(zhì)數(shù)據(jù)298-93-1(Hazardous Substances Data)
應(yīng)用領(lǐng)域
用途1
1．藥物（也包括其他處理方式如放射線照射）對(duì)體外培養(yǎng)的細(xì)胞毒性的測(cè)定；
2．細(xì)胞增殖及細(xì)胞活性測(cè)定。噻唑藍(lán)價(jià)格(試劑級(jí))
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱(chēng) | CAS號(hào) | 包裝 | 價(jià)格 |
| 2024/11/08 | L11939 | 噻唑藍(lán)溴化四唑, 98% Thiazolyl Blue tetrazolium bromide, 98% | 298-93-1 | 1g | 526元 |
| 2024/11/08 | L11939 | 噻唑藍(lán)溴化四唑, 98% Thiazolyl Blue tetrazolium bromide, 98% | 298-93-1 | 5g | 1949元 |
| 2024/11/08 | 15899 | 噻唑藍(lán)溴化四唑 Thiazolyl blue tetrazolium bromide, 98%, Thermo Scientific Chemicals | 298-93-1 | 250mg | 617元 |
常見(jiàn)問(wèn)題列表
生物活性
Thiazolyl Blue (MTT, Tetrazolium bromide, Methylthiazolyldiphenyl-tetrazolium bromide, Methylthialazole Tetrazolium)是一種細(xì)胞可滲透且?guī)д姷谋壬珓粡V泛用于檢測(cè)細(xì)胞中的還原代謝以及測(cè)量細(xì)胞增殖，細(xì)胞毒性和凋亡。Thiazolyl Blue (MTT) 在活細(xì)胞中會(huì)從黃色還原為紫色的甲臜。體外研究
Thiazolyl Blue (MTT) is used in conjunction with rhodamine B to measure mitochondrial membrane potential. Thiazolyl Blue-formazan is generated in mitochondria acts as a fluorescence quencher for rhodamine that distributes across membranes of viable cells according to membrane potential. In the absence of mPMS, cellular reduction of Thiazolyl Blue is strong. Thiazolyl Blue is membrane-impermeable when incorporated into large unilamellar liposomes, and therefore it is taken up by cells via endocytosis.