2364-67-2
2364-67-2 結(jié)構(gòu)式
基本信息
中文別名
棕櫚酰-L-左旋肉堿 英文別名
C02990Palmitylcarnitine
L-Palmitoylcarnitine
Palmityl-L-carnitine
Palmitoyl L-carnitine
Hexadecanoylcarnitine
O-palmitoyl-L-carnitine
Palmitoyl-L-Carnitine solution
Palmitoyl-L-carnitine >=97.0% (TLC)
(3R)-3-hexadecanoyloxy-4-trimethylazaniumylbutanoate
棕櫚酰肉堿價(jià)格(試劑級)
| 報(bào)價(jià)日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價(jià)格 |
| 2022/07/01 | HY-113147 | 棕櫚酰肉堿 L-Palmitoylcarnitine | 2364-67-2 | 5 mg | 1500元 |
常見問題列表
生物活性
L-Palmitoylcarnitine 是一種長鏈?；鈮A和脂肪酸代謝產(chǎn)物，在缺血期間積聚于肌膜并擾亂膜脂環(huán)境。L-Palmitoylcarnitine 通過與 Kir6.2 的相互作用抑制 KATP 通道活性，而不影響單通道電導(dǎo)。靶點(diǎn)
|
Kir6.2
|
Human Endogenous Metabolite
|
體外研究
L-Palmitoylcarnitine (1 μM) inhibits K
ATP
channel activity, without affecting the single channel conductance, through interaction with Kir6.2. L-Palmitoylcarnitine simultaneously enhances the ATP sensitivity of the channel (IC
50
fell from 62 to 30 μM).
Modulation of the membrane lipid environment caused by L-Palmitoylcarnitine alters the K
ATP
channel function mainly through the interaction with endogenous PI cascade, especially PIP2.