2222112-77-6
中文名稱
ARV110
英文名稱
3-Pyridazinecarboxamide, N-[trans-4-(3-chloro-4-cyanophenoxy)cyclohexyl]-6-[4-[[4-[2-(2,6-dioxo-3-piperidinyl)-6-fluoro-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]-1-piperazinyl]methyl]-1-piperidinyl]-
CAS
2222112-77-6
分子式
C41H43ClFN9O6
分子量
812.29
MOL 文件
2222112-77-6.mol
更新日期
2024/11/07 11:01:32
2222112-77-6 結(jié)構(gòu)式
基本信息
中文別名
ARV110N-[反式-4-(3-氯-4-氰基苯氧基)環(huán)己基]-6-[4-[[4-[2-(2,6-二氧-3-哌啶基)-6-氟] -2,3-二氫-1,3-二氧-1H-異吲哚-5-基]-1-哌嗪基]甲基]-1-哌啶基]-3-噠嗪甲酰胺
英文別名
ARV-110N-((1R,4R)-4-(3-chloro-4-cyanophenox y)cyclohexyl)-6-(4-((4-(2-(2,6-dioxopip eridin-3-yl)-6-fluoro-1,3-dioxoisoindoli n-5-yl)piperazin-1-yl)methyl)piperidin-1 -yl)pyridazine-3-carboxamide
3-Pyridazinecarboxamide, N-[trans-4-(3-chloro-4-cyanophenoxy)cyclohexyl]-6-[4-[[4-[2-(2,6-dioxo-3-piperidinyl)-6-fluoro-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]-1-piperazinyl]methyl]-1-piperidinyl]-
物理化學(xué)性質(zhì)
沸點(diǎn)1074.1±65.0 °C(Predicted)
密度1.49±0.1 g/cm3(Predicted)
儲存條件Store at-20°C, away from moisture
溶解度DMSO : 26.67 mg/mL (32.83 mM; ultrasonic and warming and adjust pH to 3 with HCl and heat to 80°C)
酸度系數(shù)(pKa)10.59±0.40(Predicted)
形態(tài)Solid
顏色Light yellow to yellow