1874-54-0
1874-54-0 結(jié)構(gòu)式
基本信息
中文別名
阿洛酮糖腺苷 英文別名
U-9586NSC 53104
psicofuranin
psicofuranine
Angustmycin C
Psicofuranosyladenine
1'-(Hydroxymethyl)adenosine
Psicofuranine [AngustMycin C]
9-beta-D-Psicofuranosyladenine
Adenosine, 1'-C-(hydroxymethyl)-
物理化學(xué)性質(zhì)
熔點(diǎn)212-214℃ (decomposition)
比旋光度D25 -68° (dimethylformamide)
沸點(diǎn)720.1±70.0 °C(Predicted)
密度2.02±0.1 g/cm3(Predicted)
儲(chǔ)存條件-20°C儲(chǔ)存
溶解度溶于二甲基亞砜
酸度系數(shù)(pKa)12.87±0.70(Predicted)
形態(tài)固體
顏色白色至灰白色
阿洛酮糖腺苷價(jià)格(試劑級)
| 報(bào)價(jià)日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價(jià)格 |
| 2024/11/08 | HY-119819 | 阿洛酮糖腺苷 Psicofuranine | 1874-54-0 | 1mg | 2340元 |
常見問題列表
生物活性
Psicofuramine 是一種核苷抗生素，具有抑制黃嘌呤 5'-磷酸氨化酶的作用。Psicofuramine 還可以特異性抑制 GMP 合酶，并中斷寄生蟲的生長。Psicofuramine 對惡性瘧原蟲的生長具有劑量依賴性抑制作用。靶點(diǎn)
Xanthosine 5'-phosphate aminase
P. falciparum
E. coli
體外研究
Psicofuranine specifically inhibits bacterial GMP synthase as demonstrated by isolation of Psicofuranine-resistant Escherichia coli mutants with mutations in the gene encoding GMP synthase and inhibition of bacterial growth. Psicofuranine exhibits a dose-dependent inhibition of P. falciparum growth with an IC 50 of 0.3 mM. The Psicofuranine inhibitory concentration is similar to that of E. coli .