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186319-72-2

英文名稱 β-Amyloid (1-17)
CAS 186319-72-2
分子式 C90H130N28O29
分子量 2068.17
MOL 文件 186319-72-2.mol
186319-72-2 結(jié)構(gòu)式 186319-72-2 結(jié)構(gòu)式

基本信息

英文別名
β-Amyloid 1-17
β-Amyloid (1-17)
L-Leucine, L-α-aspartyl-L-alanyl-L-α-glutamyl-L-phenylalanyl-L-arginyl-L-histidyl-L-α-aspartyl-L-serylglycyl-L-tyrosyl-L-α-glutamyl-L-valyl-L-histidyl-L-histidyl-L-glutaminyl-L-lysyl-

物理化學性質(zhì)

儲存條件-20°C儲存
溶解度溶于二甲基亞砜

常見問題列表

生物活性
β-Amyloid (1-17) 是一種 β-Amyloid 的多肽片段,能夠穩(wěn)定纖維,在 Aβ 纖維形成過程中具有重要作用。
體外研究

β-Amyloid Aggregation Guidelines (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs).
1. Solid Aβ peptide was dissolved in cold hexafluoro-2-propanol (HFIP). The peptide was incubated at room temperature for at least 1h to establish monomerization and randomization of structure.
2. The HFIP was removed by evaporation, and the resulting peptide was stored as a film at -20 or -80 ℃.
3. The resulting film was dissolved in anhydrous DMSO at 5 mM and then diluted into the appropriate concentration and buffer (serum- and phenol red-free culture medium) with vortexing.
4. Next, the solution was age 48h at 4-8 ℃. The sample was then centrifuged at 14000g for 10 min at 4-8 ℃; the soluble oligomers were in the supernatant. The supernatant was diluted 10-200-fold for experiments.
Methods vary depends on the downstream applications.

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